DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yun, Hyungdon | ko |
dc.contributor.author | Yang, Yung-Hun | ko |
dc.contributor.author | Cho, Byung-Kwan | ko |
dc.contributor.author | Hwang, Bum-Yeol | ko |
dc.contributor.author | Kim, Byung-Gee | ko |
dc.date.accessioned | 2013-03-04T00:35:59Z | - |
dc.date.available | 2013-03-04T00:35:59Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2003-05 | - |
dc.identifier.citation | BIOTECHNOLOGY LETTERS, v.25, no.10, pp.809 - 814 | - |
dc.identifier.issn | 0141-5492 | - |
dc.identifier.uri | http://hdl.handle.net/10203/81107 | - |
dc.description.abstract | A simultaneous synthesis of (R)-1-phenylethanol and (R)-alpha-methylbenzylamine from racemic a-methylbenzylamine was achievied using omega-transaminase, alcohol dehydrogenase, and glucose dehydrogenase in a coupled reaction. Racemic alpha-methylbenzylamine (100 mM) was converted to 49 mM (R)-1-phenylethanol (> 99% ee) and 48 mM (R)-alpha-methylbenzylamine (> 98% ee) in 18 h at 37 degreesC. This method was also used to overcome product inhibition of omega-TA by the ketone product in the kinetic resolution of racemic amines at high concentration. | - |
dc.language | English | - |
dc.publisher | SPRINGER | - |
dc.subject | KINETIC RESOLUTION | - |
dc.subject | ALCOHOL-DEHYDROGENASE | - |
dc.subject | GLUCOSE-DEHYDROGENASE | - |
dc.subject | BACILLUS-SUBTILIS | - |
dc.subject | CELLS | - |
dc.subject | CATALYST | - |
dc.subject | SYSTEM | - |
dc.title | Simultaneous synthesis of enantiomerically pure (R)-1-phenylethanol and (R)-alpha-methylbenzylamine from racemic alpha-methylbenzylamine using omega-transaminase/alcohol dehydrogenase/glucose dehydrogenase coupling reaction | - |
dc.type | Article | - |
dc.identifier.wosid | 000182521100011 | - |
dc.identifier.scopusid | 2-s2.0-0038242206 | - |
dc.type.rims | ART | - |
dc.citation.volume | 25 | - |
dc.citation.issue | 10 | - |
dc.citation.beginningpage | 809 | - |
dc.citation.endingpage | 814 | - |
dc.citation.publicationname | BIOTECHNOLOGY LETTERS | - |
dc.identifier.doi | 10.1023/A:1023500406897 | - |
dc.contributor.localauthor | Cho, Byung-Kwan | - |
dc.contributor.nonIdAuthor | Yun, Hyungdon | - |
dc.contributor.nonIdAuthor | Yang, Yung-Hun | - |
dc.contributor.nonIdAuthor | Hwang, Bum-Yeol | - |
dc.contributor.nonIdAuthor | Kim, Byung-Gee | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | alcohol dehydrogenase | - |
dc.subject.keywordAuthor | glucose dehydrogenase | - |
dc.subject.keywordAuthor | kinetic resolution | - |
dc.subject.keywordAuthor | NADPH regeneration | - |
dc.subject.keywordAuthor | omega-transaminase | - |
dc.subject.keywordPlus | KINETIC RESOLUTION | - |
dc.subject.keywordPlus | ALCOHOL-DEHYDROGENASE | - |
dc.subject.keywordPlus | GLUCOSE-DEHYDROGENASE | - |
dc.subject.keywordPlus | BACILLUS-SUBTILIS | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | CATALYST | - |
dc.subject.keywordPlus | SYSTEM | - |
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