Ni-base Alloy 600 has been widely used as a steam generator (SIG) tubing material in nuclear power plants because of its good mechanical and corrosion properties at high temperatures. However, degradations of SIG tubes due to intergranular attack (IGA) and intergranular stress corrosion cracking (IGSCC) during normal operation were frequently reported. in particular, Alloy 600 can be very susceptible to IGA/IGSCC in some sulfur-bearing environments by sensitization. In this paper, the beneficial effects of laser surface melting (LSM) to intergranular corrosion of the sensitized Alloy 600 is presented from the results of the double loop electrochemical potentiokinetic reactivation (DL-EPR) test. The DL-EPR test was performed in de-aerated 0.01 M H2SO4 + 20 ppm KSCN at a scan rate of 0.5 mV/sec at room temperature. The degree of sensitization (DOS) of the sensitized Alloy 600 measured from the DL-EPR test was considerably reduced by LSM. The sensitized Alloy 600 after LSM also exhibited a relatively low DOS, comparing with that of the sensitized but not laser treated Alloy 600. From the microscopic observation, it was found that the microstructural changes by the LSM process, especially changes in the precipitation behavior of grain boundary Cr-rich carbides, caused the improvement of resistance to intergranular corrosion of the laser treated Alloy 600. The resistance to IGSCC of the laser treated Alloy 600 in sulfur-bearing environments was also discussed from the results of measured DOS and microstructural examination.