When four photons arrive at a beam splitter, two from each side, a four-photon, six-path interference effect occurs to yield a sixfold enhancement of the probability for all four photons to exit together from the beam splitter. We produce the four-photon state by using the stimulated emission process in a pulsed parametric down-conversion and measure the probability for all four photons to exit from one side of the beam splitter. The observed enhancement factor is in good agreement with a multimode treatment of pulsed down-conversion.