Transcriptional activation in yeast by the proline-rich domain of human CTF1

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Among eukaryotic transcriptional activators, those with acidic activation domains have been shown to stimulate transcription in organisms ranging from yeast to human. In vivo and in vitro assays have been employed to demonstrate transcriptional enhancement in yeast by the proline-rich activation domain of human CTF1. This result suggests that proline-rich activation domains may, like typical acidic activation domains, functional universally.
Publisher
Amer Soc Biochemistry Molecular Biology Inc
Issue Date
1993-10
Language
English
Article Type
Article
Keywords

RNA POLYMERASE-II; SACCHAROMYCES-CEREVISIAE; PREINITIATION COMPLEX; GAL4 DERIVATIVES; BINDING PROTEINS; GLUTAMINE-RICH; TFIID COMPLEX; INVITRO; DNA; COACTIVATORS

Citation

JOURNAL OF BIOLOGICAL CHEMISTRY, v.268, no.28, pp.20866 - 50869

ISSN
0021-9258
URI
http://hdl.handle.net/10203/59120
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