In order to formulate an effective information system investment plan of a company, it is important to recognize the priority of the company’s information systems and the characteristics of its business strategy. For different business strategy leads a company to different IS strategy, this article presents a method to reflect corporate business strategy for prioritizing and assessing different information systems. The model, which is loosely based on quality function deployment (QFD), incorporates corporate business strategy, information systems characteristics as rows and columns of QFD matrix. In addition, analytic hierarchy process (AHP) is used to determine the intensity of the relationship between the row and column variables of the matrix. Finally, the applicability of the proposed method is demonstrated with a case study that summarizes an intervention in which the model’s framework and basic concepts were applied.