DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Kim, Sung-Gak | - |
dc.contributor.advisor | 김성각 | - |
dc.contributor.author | Kim, Nam-Seon | - |
dc.contributor.author | 김남선 | - |
dc.date.accessioned | 2011-12-13T04:46:54Z | - |
dc.date.available | 2011-12-13T04:46:54Z | - |
dc.date.issued | 1999 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=151661&flag=dissertation | - |
dc.identifier.uri | http://hdl.handle.net/10203/31802 | - |
dc.description | 학위논문(석사) - 한국과학기술원 : 화학과, 1999.2, [ iii, 57 p. ] | - |
dc.description.abstract | The intermolecular addition of alkyl iodides to phenylsulfonyl oxime ether derivatives afforded the aldehydes, ketones, α-keto ester and 1,2-diketone in good yield. The various carbocyclic ketones, and acyclic ketones via sequential radical acylation approach using bis-methylsulfonyl oxime ether were prepared. The radical acylation reaction of O-bensyl-3-iodo-1-methylsulfonyl-propanaldoxime or O-benzyl-4-iodo-1-methylsulfonyl-butanaldoxime with alkene and hexamethylditin afforded α-substituted 5-and 6-membered cyclic ketone in good yield. Radical acylation reaction with alkyne the acylating compounds, so we could obtaine α,β-unsaturated cyclic oxime and protected lactam. All oxime ethers were easily hydrolyzed to the corresponding ketone under acidic condition. Bis-methylsulfonyl oxime ether reacted with various nucleophiles such as: enolates of esters, ketones and α-anions of sulfone. Radical acylation reactions of alkyl iodides with the substituted methylsulfonyl oxime ethers were proceded smoothly, yielding β-keto ester, 1,3-diketone, protected β-keto sulfone and protected lactone through radical acylation reaction. | eng |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | Radical cyclization | - |
dc.subject | Oxime ether derivatives | - |
dc.subject | β-Keto ester | - |
dc.subject | β-케토 에스터 | - |
dc.subject | 라디칼 고리화반응 | - |
dc.subject | 옥심에테르 유도체 | - |
dc.title | Radical reaction of oxime ether derivatives | - |
dc.title.alternative | 옥심에테르 유도체를 이용한 라디칼 반응 | - |
dc.type | Thesis(Master) | - |
dc.identifier.CNRN | 151661/325007 | - |
dc.description.department | 한국과학기술원 : 화학과, | - |
dc.identifier.uid | 000973058 | - |
dc.contributor.localauthor | Kim, Sung-Gak | - |
dc.contributor.localauthor | 김성각 | - |
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