DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Jeehee | ko |
dc.contributor.author | Park, Eunsook | ko |
dc.contributor.author | Lee, Kyueui | ko |
dc.contributor.author | Shin, Mikyung | ko |
dc.contributor.author | Lee, Soohyeon | ko |
dc.contributor.author | Moreno-Villaecija, Miguel Angel | ko |
dc.contributor.author | Lee, Haeshin | ko |
dc.date.accessioned | 2023-03-13T06:01:33Z | - |
dc.date.available | 2023-03-13T06:01:33Z | - |
dc.date.created | 2023-03-13 | - |
dc.date.issued | 2023-01 | - |
dc.identifier.citation | ACTA BIOMATERIALIA, v.155, pp.247 - 257 | - |
dc.identifier.issn | 1742-7061 | - |
dc.identifier.uri | http://hdl.handle.net/10203/305586 | - |
dc.description.abstract | Plants release phenolic molecules to protect against invading pathogens. In plant-microorganism rela-tionships, phenolics bind to surface oligosaccharides, inactivating microorganism activities. Inspired by phenol-saccharide interactions in plant defense systems, we designed an adhesive sealant. By screening 16 different saccharides, the O-acetyl group, rich in glucomannan (GM), exhibited rapid, robust bind-ing with the galloyl moiety of a model phenolic molecule, tannic acid (TA). Furthermore, the interaction showed both pH and temperature (upper critical solution temperature) sensitivities. Utilizing O-acetyl-galloyl interactions, materials of all dimensions from beads (0D) to strings (1D), films (2D), and objects (3D) could be prepared, as a suitable platform for printing techniques. GMTA films are elastic, adhesive, water-resistant, and effectively sealed perforations, as demonstrated by (1) a lung incision followed by an air inflation model and (2) a thoracic diaphragm model.Statement of significanceIn nature, phenolic molecules are 'nearly always' physically bound with polysaccharides, indicating that the phenolics widen the functions of polysaccharides. An example includes that phenolic-polysaccharide interactions are key defense mechanisms against microbial infection in plants whereas polysaccharide alone functions poorly. Despite the ubiquitous biochemistry of polysaccharide-phenolic interactions, ef-forts on understanding binding chemistry focusing on phenol/polysaccharide interactions is little. This study is important because we found for the first time that O-acetyl group is the moiety in polysaccha-rides to which phenolic cis-diol and/or cis-triol is spontaneously bound. The phenol-polysaccharide inter-action is non-covalent yet robust, kinetically fast, and reversible. Inspired by the interaction chemistry, a simple mixture of phenolic molecules and O-acetyl group containing polysaccharides such as glucoman-nan opens a promising fabrication strategy toward functional polysaccharide-based material.(c) 2022 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.title | Reversible tissue sticker inspired by chemistry in plant-pathogen relationship | - |
dc.type | Article | - |
dc.identifier.wosid | 000923183000001 | - |
dc.identifier.scopusid | 2-s2.0-85142837445 | - |
dc.type.rims | ART | - |
dc.citation.volume | 155 | - |
dc.citation.beginningpage | 247 | - |
dc.citation.endingpage | 257 | - |
dc.citation.publicationname | ACTA BIOMATERIALIA | - |
dc.identifier.doi | 10.1016/j.actbio.2022.09.075 | - |
dc.contributor.localauthor | Lee, Haeshin | - |
dc.contributor.nonIdAuthor | Lee, Jeehee | - |
dc.contributor.nonIdAuthor | Lee, Kyueui | - |
dc.contributor.nonIdAuthor | Shin, Mikyung | - |
dc.contributor.nonIdAuthor | Lee, Soohyeon | - |
dc.contributor.nonIdAuthor | Moreno-Villaecija, Miguel Angel | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Polysaccharide | - |
dc.subject.keywordAuthor | Phenol | - |
dc.subject.keywordAuthor | O-acetyl | - |
dc.subject.keywordAuthor | Bio-inspired | - |
dc.subject.keywordAuthor | Hydrogen bonding | - |
dc.subject.keywordPlus | TANNIC-ACID | - |
dc.subject.keywordPlus | MICROCYSTIS-AERUGINOSA | - |
dc.subject.keywordPlus | KONJAC GLUCOMANNAN | - |
dc.subject.keywordPlus | GENE-EXPRESSION | - |
dc.subject.keywordPlus | POLYPHENOLS | - |
dc.subject.keywordPlus | ANTIOXIDANT | - |
dc.subject.keywordPlus | CONSEQUENCES | - |
dc.subject.keywordPlus | HYDROGELS | - |
dc.subject.keywordPlus | ADHESIVE | - |
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