Urea removal from dialysates in anion-transfer menbrane enzyme reactor = Anion-transfer membrane 을 이용한 효소 반응기내에서의 dialysates 로 부터의 요소 제거

Cited 0 time in webofscience Cited 0 time in scopus
  • Hit : 267
  • Download : 0
Improved urea removal system utilizing Anion Transfer Membrane (A.T.M.) is investigated. The A.T.M. selectively passes the urea and anions but it prevents the passage of electrolytes essential for the body and toxic ammonium ion. The overall membrane resistances of A.T.M. are determined by a dual closed-loop technique. Using 0.2 M sodium phosphate citrate buffer, effects of urease enzyme concentration on urea removal and effects of activators such as DL-alanine and glycine on urea removal are investigated. Comparison with other urea removal systems are made by simulation using two compartment model. Experimental results showed that 1.5 unit/ml urease enzyme concentration is adequate for the system of 0.5 L. blood bath and 0.5 L. dialysate bath. Effects of activators was not observed probably owing to very low urea concentration in dialysate. The simulation has been shown that A.T.M. system is more efficient than other system in urea removal and toxic ammonium ion removal. Very low ammonium ion concentration (16$\mu$G/L) in extracellular fluid is obtained, but absolute prevention of ammonium ion passage is not achieved unless adsorbent for ammonium ion is not used. The results suggest further work for developments of A.T.M. for artificial kidney use.
Advisors
Chang, Ho-Namresearcher장호남researcher
Description
한국과학기술원 : 화학공학과,
Publisher
한국과학기술원
Issue Date
1980
Identifier
62655/325007 / 000781052
Language
eng
Description

학위논문 (석사) - 한국과학기술원 : 화학공학과, 1980.2, [ iv, 63 p. ]

URI
http://hdl.handle.net/10203/30086
Link
http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=62655&flag=dissertation
Appears in Collection
CBE-Theses_Master(석사논문)
Files in This Item
There are no files associated with this item.

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0