A novel method for miRNA detection based on target-triggered transcription of a light-up RNA aptamer
We herein describe a novel method for miRNA detection based on target-triggered transcription of a light-up RNA aptamer (TTRApt), consequently producing a highly enhanced fluorescence signal through specific binding of a light-up RNA aptamer to the corresponding dye. Using this strategy, we successfully identified target miRNA down to 59.4 aM with excellent specificity.
- Publisher
- ROYAL SOC CHEMISTRY
- Issue Date
- 2022-03
- Language
- English
- Article Type
- Article
- Citation
CHEMICAL COMMUNICATIONS, v.58, no.26, pp.4243 - 4246
- ISSN
- 1359-7345
- Appears in Collection
- CBE-Journal Papers(저널논문)
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