Designing SERS-active Microgels through Simultaneous Photoreduction and Photocross-linking for Direct Raman Analysis of Target Molecules

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dc.contributor.author윤지원ko
dc.contributor.author김동재ko
dc.contributor.author김동호ko
dc.contributor.author박성규ko
dc.contributor.author김신현ko
dc.date.accessioned2021-11-10T06:45:06Z-
dc.date.available2021-11-10T06:45:06Z-
dc.date.created2021-11-09-
dc.date.issued2021-11-05-
dc.identifier.citation2021 한국공업화학회 추계 총회 및 학술대회-
dc.identifier.urihttp://hdl.handle.net/10203/289068-
dc.description.abstractSurface-enhanced Raman scattering (SERS) induced by metal nanoparticles (NPs) or nanostructures is a key to overcoming the low Raman signal. However, metal surface being vulnerable to contamination by protein makes it challenging to detect only target molecules in a complex medium. Herein, we design plasmonic microgels through simultaneous photoreduction and photocross-linking. Water-in-oil (W/O) emulsions are produced using microfluidics. Emulsions are irradiated to form hydrogel network and gold nanoparticles. Here, hydrogel network serves as a filter to exclude protein, which is larger than the pore size of PEGDA mesh. Under the heat, unreacted gold precursor is reduced by sodium citrate, leading to the formation of new gold NPs or the growth of pre-formed gold NPs. Concentration of sodium citrate is optimized for SERS sensitivity and microgels show SERS signal uniformity. As a proof of concept, we successfully detected a biomarker of sepsis called pyocyanin from saliva.-
dc.languageKorean-
dc.publisher한국공업화학회-
dc.titleDesigning SERS-active Microgels through Simultaneous Photoreduction and Photocross-linking for Direct Raman Analysis of Target Molecules-
dc.typeConference-
dc.type.rimsCONF-
dc.citation.publicationname2021 한국공업화학회 추계 총회 및 학술대회-
dc.identifier.conferencecountryKO-
dc.identifier.conferencelocation대구 EXCO-
dc.contributor.localauthor김신현-
dc.contributor.nonIdAuthor김동재-
dc.contributor.nonIdAuthor김동호-
dc.contributor.nonIdAuthor박성규-
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CBE-Conference Papers(학술회의논문)
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