DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Moon-Il | ko |
dc.contributor.author | Park, Chan Yeong | ko |
dc.contributor.author | Seo, Ji Min | ko |
dc.contributor.author | Kang, Kyoung Suk | ko |
dc.contributor.author | Park, Ki Soo | ko |
dc.contributor.author | Kang, Jongeun | ko |
dc.contributor.author | Hong, Kwan Soo | ko |
dc.contributor.author | Choi, Yoojin | ko |
dc.contributor.author | Lee, Sang Yup | ko |
dc.contributor.author | Park, Jong Pil | ko |
dc.contributor.author | Park, Hyun Gyu | ko |
dc.contributor.author | Park, Tae Jung | ko |
dc.date.accessioned | 2021-08-13T07:10:08Z | - |
dc.date.available | 2021-08-13T07:10:08Z | - |
dc.date.created | 2021-08-13 | - |
dc.date.created | 2021-08-13 | - |
dc.date.created | 2021-08-13 | - |
dc.date.created | 2021-08-13 | - |
dc.date.created | 2021-08-13 | - |
dc.date.created | 2021-08-13 | - |
dc.date.issued | 2021-07 | - |
dc.identifier.citation | ACS APPLIED MATERIALS & INTERFACES, v.13, no.31, pp.36697 - 36708 | - |
dc.identifier.issn | 1944-8244 | - |
dc.identifier.uri | http://hdl.handle.net/10203/287166 | - |
dc.description.abstract | Development of drug-delivery systems that allow simultaneous in vivo imaging has gained much interest. We report a novel strategy to encapsulate metal nanoparticles (NPs) within alginate gel for in vivo imaging. The cell lysate of recombinant Escherichia coli strain, expressing Arabidopsis thaliana phytochelatin synthase and Pseudomonas putida metallothionein genes, was encapsulated within the alginate gel. Incubation of alginate gel with metal ion precursors followed by UV irradiation resulted in the synthesis of high concentrations of metal NPs, such as Au, Ag, CdSe, and EuSe NPs, within the gel. The alginate gel with metal NPs was used as a drug-delivery system by further co-encapsulating doxorubicin and rifampicin, the release of which was made to be pH-dependent. This system can be conveniently and safely used for in vitro and in vivo bioimaging, enabled by the metal NPs formed within the gel matrix without using toxic reducing reagents or surfactants. | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | In Situ Biosynthesis of a Metal Nanoparticle Encapsulated in Alginate Gel for Imageable Drug-Delivery System | - |
dc.type | Article | - |
dc.identifier.wosid | 000685245800004 | - |
dc.identifier.scopusid | 2-s2.0-85112565355 | - |
dc.type.rims | ART | - |
dc.citation.volume | 13 | - |
dc.citation.issue | 31 | - |
dc.citation.beginningpage | 36697 | - |
dc.citation.endingpage | 36708 | - |
dc.citation.publicationname | ACS APPLIED MATERIALS & INTERFACES | - |
dc.identifier.doi | 10.1021/acsami.1c02286 | - |
dc.contributor.localauthor | Lee, Sang Yup | - |
dc.contributor.localauthor | Park, Hyun Gyu | - |
dc.contributor.nonIdAuthor | Kim, Moon-Il | - |
dc.contributor.nonIdAuthor | Park, Chan Yeong | - |
dc.contributor.nonIdAuthor | Seo, Ji Min | - |
dc.contributor.nonIdAuthor | Park, Ki Soo | - |
dc.contributor.nonIdAuthor | Kang, Jongeun | - |
dc.contributor.nonIdAuthor | Hong, Kwan Soo | - |
dc.contributor.nonIdAuthor | Choi, Yoojin | - |
dc.contributor.nonIdAuthor | Park, Jong Pil | - |
dc.contributor.nonIdAuthor | Park, Tae Jung | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | alginate gel | - |
dc.subject.keywordAuthor | biogenic metal nanoparticle | - |
dc.subject.keywordAuthor | in situ synthesis | - |
dc.subject.keywordAuthor | bioimaging | - |
dc.subject.keywordAuthor | drug-delivery system | - |
dc.subject.keywordPlus | PHYTOCHELATIN-SYNTHASE | - |
dc.subject.keywordPlus | GOLD NANOPARTICLES | - |
dc.subject.keywordPlus | VIVO SYNTHESIS | - |
dc.subject.keywordPlus | ION-EXCHANGE | - |
dc.subject.keywordPlus | TRANSFORMATION | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | BEHAVIOR | - |
dc.subject.keywordPlus | SELENIUM | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.