Pushbutton-activated microfluidic cartridge as a user-friendly sample preparation tool for diagnostics

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Microfluidic technologies have several advantages in sample preparation for diagnostics but suffer from the need for an external operation system that hampers user-friendliness. To overcome this limitation in microfluidic technologies, a number of user-friendly methods utilizing capillary force, degassed poly(dimethylsiloxane), pushbutton-driven pressure, a syringe, or a pipette have been reported. Among these methods, the pushbutton-driven, pressure-based method has a great potential to be widely used as a user-friendly sample preparation tool for point-of-care testing or portable diagnostics. In this Perspective, we focus on the pushbutton-activated microfluidic technologies toward a user-friendly sample preparation tool. The working principle and recent advances in pushbutton-activated microfluidic technologies are briefly reviewed, and future perspectives for wide application are discussed in terms of integration with the signal analysis system, user-dependent variation, and universal and facile use.
Publisher
AMER INST PHYSICS
Issue Date
2021-07
Language
English
Article Type
Article
Citation

BIOMICROFLUIDICS, v.15, no.4, pp.041302

ISSN
1932-1058
DOI
10.1063/5.0056580
URI
http://hdl.handle.net/10203/286772
Appears in Collection
BiS-Journal Papers(저널논문)
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