DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ma, Danyi | ko |
dc.contributor.author | Yu, Qianqian | ko |
dc.contributor.author | Hedrick, Victoria E. | ko |
dc.contributor.author | Cooper, Bruce R. | ko |
dc.contributor.author | Sobreira, Tiago Jose Paschoal | ko |
dc.contributor.author | Oh, Ji-Hwan | ko |
dc.contributor.author | Chun, Hyonho | ko |
dc.contributor.author | Kim, Yuan H. Brad | ko |
dc.date.accessioned | 2021-03-04T00:30:07Z | - |
dc.date.available | 2021-03-04T00:30:07Z | - |
dc.date.created | 2021-02-24 | - |
dc.date.created | 2021-02-24 | - |
dc.date.created | 2021-02-24 | - |
dc.date.created | 2021-02-24 | - |
dc.date.issued | 2020-08 | - |
dc.identifier.citation | MEAT SCIENCE, v.166, pp.108140 | - |
dc.identifier.issn | 0309-1740 | - |
dc.identifier.uri | http://hdl.handle.net/10203/281156 | - |
dc.description.abstract | Proteome and metabolome changes in muscles from callipyge mutation (+/C) and non-callipyge phenotype (+/+, C/+, and C/C) lambs were profiled to provide insight into the biochemical changes affecting meat quality attributes. M. longissimus thoracis from lambs with all four possible callipyge genotype (n= 4, C/+, C/C, +/C, and +/+) were collected after 3d aging and analyzed using mass-spectrometry based platforms. Among identified proteomes, cytochrome c (pro-apoptotic protein) was detected with significantly lower abundances in +/C. Anti-apoptotic HSP70, BAG3, and PARK7 were over-abundant in +/C, which could result in delayed apoptosis and possibly attributed to tougher meat in callipyge lambs. Eight glycolysis enzymes were overabundant in +/C lambs, whereas 3 enzymes involved in TCA cycle were overabundant in non-callipyge ones (C/C and/or C/+). Twenty-five metabolites were affected by genotypes (P <.05), including metabolic co-factors, polyphenols, and AA/short peptides. Our omics results provided insightful information for revealing the differences in biochemical attributes caused by callipyge mutation. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.title | Proteomic and metabolomic profiling reveals the involvement of apoptosis in meat quality characteristics of ovine M. longissimus from different callipyge genotypes | - |
dc.type | Article | - |
dc.identifier.wosid | 000535862900015 | - |
dc.identifier.scopusid | 2-s2.0-85083002414 | - |
dc.type.rims | ART | - |
dc.citation.volume | 166 | - |
dc.citation.beginningpage | 108140 | - |
dc.citation.publicationname | MEAT SCIENCE | - |
dc.identifier.doi | 10.1016/j.meatsci.2020.108140 | - |
dc.contributor.localauthor | Chun, Hyonho | - |
dc.contributor.nonIdAuthor | Ma, Danyi | - |
dc.contributor.nonIdAuthor | Yu, Qianqian | - |
dc.contributor.nonIdAuthor | Hedrick, Victoria E. | - |
dc.contributor.nonIdAuthor | Cooper, Bruce R. | - |
dc.contributor.nonIdAuthor | Sobreira, Tiago Jose Paschoal | - |
dc.contributor.nonIdAuthor | Oh, Ji-Hwan | - |
dc.contributor.nonIdAuthor | Kim, Yuan H. Brad | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Proteomics | - |
dc.subject.keywordAuthor | Metabolomics | - |
dc.subject.keywordAuthor | Apoptosis | - |
dc.subject.keywordAuthor | Callipyge lambs | - |
dc.subject.keywordPlus | CHROMATOGRAPHY-MASS SPECTROMETRY | - |
dc.subject.keywordPlus | MUSCLE-FIBER CHARACTERISTICS | - |
dc.subject.keywordPlus | CYTOCHROME-C | - |
dc.subject.keywordPlus | PHENOTYPIC CHARACTERIZATION | - |
dc.subject.keywordPlus | POLAR OVERDOMINANCE | - |
dc.subject.keywordPlus | PROTEIN-DEGRADATION | - |
dc.subject.keywordPlus | CALPAIN INHIBITOR | - |
dc.subject.keywordPlus | POSTMORTEM | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordPlus | ATTRIBUTES | - |
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