세포 운동 가시화를 통한 상처 치유 과정 내 경계 이동의 규명

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dc.contributor.author정현태ko
dc.contributor.author이재성ko
dc.contributor.author신현정ko
dc.date.accessioned2021-02-04T05:50:04Z-
dc.date.available2021-02-04T05:50:04Z-
dc.date.created2020-12-01-
dc.date.created2020-12-01-
dc.date.created2020-12-01-
dc.date.issued2020-08-
dc.identifier.citation한국가시화정보학회지, v.18, no.2, pp.1 - 8-
dc.identifier.issn1598-8430-
dc.identifier.urihttp://hdl.handle.net/10203/280567-
dc.description.abstractThe curvature of wound boundaries has been identified as a key modulator that determines a type of force responsible for cell migration. While several studies report how certain curvatures of the boundary correlate with the rate at which the wound closes, it remains unclear how these curvatures are spatiotemporally formed to regulate the healing process. We investigated the dynamic changes in the boundary curvatures by visualizing cell migration patterns. Locally, cells at the convex boundary continuously move forward with transmitting kinetic responses behind to the cells away from the boundary, and cells at the concave boundary exhibit dramatic contracting motion, like a purse-string, when they accumulate enough negative curvatures to gain the thrust toward the void. Globally, the dynamics of boundary geometries are controlled by the diffusive flow of cells driven by the density gradient between the wound area and the cell layer.-
dc.languageKorean-
dc.publisher한국가시화정보학회-
dc.title세포 운동 가시화를 통한 상처 치유 과정 내 경계 이동의 규명-
dc.typeArticle-
dc.type.rimsART-
dc.citation.volume18-
dc.citation.issue2-
dc.citation.beginningpage1-
dc.citation.endingpage8-
dc.citation.publicationname한국가시화정보학회지-
dc.identifier.doi10.5407/jksv.2020.18.2.010-
dc.identifier.kciidART002621607-
dc.contributor.localauthor신현정-
dc.contributor.nonIdAuthor정현태-
dc.contributor.nonIdAuthor이재성-
dc.description.isOpenAccessN-
dc.subject.keywordAuthor상처 치유-
dc.subject.keywordAuthor세포 군집 이동, 상처 경계 구조-
dc.subject.keywordAuthorWound healing-
dc.subject.keywordAuthorCollective cell migration-
dc.subject.keywordAuthorDigital Particle Image-
dc.subject.keywordAuthorVelocimetry-
dc.subject.keywordAuthorWound boundary geometry-
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ME-Journal Papers(저널논문)
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