Large scale comparative interactomics analysis of protein family networks = 단백질 패밀리 네트워크의 대규모 상호작용체 비교 연구

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dc.contributor.advisorLee, Do-Heon-
dc.contributor.advisor이도헌-
dc.contributor.authorLee, Se-Min-
dc.contributor.author이세민-
dc.date.accessioned2011-12-12T07:28:21Z-
dc.date.available2011-12-12T07:28:21Z-
dc.date.issued2005-
dc.identifier.urihttp://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=249569&flag=dissertation-
dc.identifier.urihttp://hdl.handle.net/10203/27113-
dc.description학위논문(석사) - 한국과학기술원 : 바이오시스템학과, 2005.8, [ iv, 41 p. ]-
dc.description.abstractWe carried out an extensive comparative analysis of theoretical interactomes for 146 complete genomes (archaea: 15, bacteria: 122, and eukarya: 9) using a protein structural interactome map method under a homogeneous paradigm: protein family-family interaction networks (an interactome is a set of all protein family interactions within a proteome). All the interactomes were scale-free networks, and the number of interaction pairs increased linearly along with the number of protein families. We found a fundamental difference among prokaryotic and eukaryotic interactomes: eukarya had many more hub families than archaea and bacteria, and certain special hub families characteristically determined the shape of the eukaryotic interactomes. Our finding suggests that a very small number of expansive protein families led the growth of interactomes and seemed to have played a key role in species diversification.eng
dc.languageeng-
dc.publisher한국과학기술원-
dc.subjectComparative Interactomics-
dc.subject비교상호작용체학-
dc.titleLarge scale comparative interactomics analysis of protein family networks = 단백질 패밀리 네트워크의 대규모 상호작용체 비교 연구-
dc.typeThesis(Master)-
dc.identifier.CNRN249569/325007 -
dc.description.department한국과학기술원 : 바이오시스템학과, -
dc.identifier.uid020033936-
dc.contributor.localauthorLee, Do-Heon-
dc.contributor.localauthor이도헌-
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