Synthetic Strategies for (-)-Cannabidiol and Its Structural Analogs

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dc.contributor.authorJung, Byunghyuckko
dc.contributor.authorLee, Jungkyu K.ko
dc.contributor.authorKim, Jungnamko
dc.contributor.authorKang, Eunhye K.ko
dc.contributor.authorHan, Sang Yeongko
dc.contributor.authorLee, Hee-Yoonko
dc.contributor.authorChoi, Insung S.ko
dc.date.accessioned2019-12-13T07:20:20Z-
dc.date.available2019-12-13T07:20:20Z-
dc.date.created2019-12-02-
dc.date.issued2019-11-
dc.identifier.citationCHEMISTRY-AN ASIAN JOURNAL, v.14, no.21, pp.3749 - 3762-
dc.identifier.issn1861-4728-
dc.identifier.urihttp://hdl.handle.net/10203/268844-
dc.description.abstract(-)-Cannabidiol ((-)-CBD), a non-psychoactive phytocannabinoid from Cannabis, and its structural analogs have received growing attention in recent years because of their potential therapeutic benefits, including neuroprotective, anti-epileptic, anti-inflammatory, anxiolytic, and anti-cancer properties. (-)-CBD and its analogs have been obtained mainly based on extraction from the natural source; however, the conventional extraction-based methods have some drawbacks, such as poor quality control along with purification difficulty. Chemical-synthetic strategies for (-)-CBD could tackle these issues, and, additionally, generate novel (-)-CBD analogs that exhibit advanced biological activities. This review concisely summarizes the historic and recent milestones in the synthetic strategies for (-)-CBD and its analogs.-
dc.languageEnglish-
dc.publisherWILEY-V C H VERLAG GMBH-
dc.titleSynthetic Strategies for (-)-Cannabidiol and Its Structural Analogs-
dc.typeArticle-
dc.identifier.wosid000495080600001-
dc.identifier.scopusid2-s2.0-85074348862-
dc.type.rimsART-
dc.citation.volume14-
dc.citation.issue21-
dc.citation.beginningpage3749-
dc.citation.endingpage3762-
dc.citation.publicationnameCHEMISTRY-AN ASIAN JOURNAL-
dc.identifier.doi10.1002/asia.201901179-
dc.contributor.localauthorLee, Hee-Yoon-
dc.contributor.localauthorChoi, Insung S.-
dc.contributor.nonIdAuthorJung, Byunghyuck-
dc.contributor.nonIdAuthorLee, Jungkyu K.-
dc.contributor.nonIdAuthorKang, Eunhye K.-
dc.contributor.nonIdAuthorHan, Sang Yeong-
dc.description.isOpenAccessN-
dc.type.journalArticleReview-
dc.subject.keywordAuthor(-)-cannabidiol-
dc.subject.keywordAuthorcannabidiol analogs-
dc.subject.keywordAuthorhemp plant-
dc.subject.keywordAuthormedical marijuana-
dc.subject.keywordAuthortherapeutic effects-
dc.subject.keywordPlusPLANT CANNABINOID CANNABIGEROL-
dc.subject.keywordPlusFIBER-TYPE CANNABIS-
dc.subject.keywordPlusCLAISEN REARRANGEMENT-
dc.subject.keywordPlusMOLECULAR TARGETS-
dc.subject.keywordPlusDERIVATIVES-
dc.subject.keywordPlusRECEPTOR-
dc.subject.keywordPlusACID-
dc.subject.keywordPlusEPILEPSY-
dc.subject.keywordPlusOXIDATION-
dc.subject.keywordPlusARYLATION-
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