Fiber-optic plasmonic probe with nanogap-rich Au nanoislands for on-site surface-enhanced Raman spectroscopy using repeated solid-state dewetting

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We report a fiber-optic plasmonic probe with nanogap-rich gold nanoislands for on-site surface-enhanced Raman spectroscopy (SERS). The plasmonic probe features nanogap-rich Au nanoislands on the top surface of a single multimode fiber. Au nanoislands were monolithically fabricated using repeated solid-state dewetting of thermally evaporated Au thin film. The plasmonic probe shows 7.8 x 10(6) in SERS enhancement factor and 100 nM in limit-of-detection for crystal violet under both the excitation of laser light and the collection of SERS signals through the optical fiber. The fiber-through measurement also demonstrates the label-free SERS detection of folic acid at micromolar level. The plasmonic probe can provide a tool for on-site and in vivo SERS applications. (C) The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License.
Publisher
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
Issue Date
2019-03
Language
English
Article Type
Article
Citation

JOURNAL OF BIOMEDICAL OPTICS, v.24, no.3

ISSN
1083-3668
DOI
10.1117/1.JBO.24.3.037001
URI
http://hdl.handle.net/10203/261494
Appears in Collection
BiS-Journal Papers(저널논문)
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