Monomeric avidin-like proteins with stable biotin binding ability 안정한 비오틴 결합능을 갖는 모노머형 아비딘 유사 단백질

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Disclosed are monomeric avidin-like proteins with a strong and stable biotin-binding ability, protein conjugates containing two or more of the monomeric avidin-like proteins and having a multivalent binding ability to biotin, nucleic acid molecules for encoding the monomeric avidin-like proteins, and methods for producing the monomeric avidin-like proteins, so the monomeric avidin-like proteins, due to the monomeric structure, are free from a problem of the disruption of receptor functions, caused by oligomerization occurring in existing tetrameric streptavidin or tetrameric but monovalent streptavidin variants.
Assignee
KAIST
Country
US (United States)
Issue Date
2018-07-10
Application Date
2016-06-29
Application Number
15196533
Registration Date
2018-07-10
Registration Number
10017546
URI
http://hdl.handle.net/10203/255563
Appears in Collection
CH-Patent(특허)
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