BC200 RNA: An Emerging Therapeutic Target and Diagnostic Marker for Human Cancer

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dc.contributor.authorShin, Heegwonko
dc.contributor.authorKim, Youngmiko
dc.contributor.authorKim, Meehyeinko
dc.contributor.authorLee, Younghoonko
dc.date.accessioned2019-01-23T06:55:52Z-
dc.date.available2019-01-23T06:55:52Z-
dc.date.created2019-01-14-
dc.date.created2019-01-14-
dc.date.issued2018-12-
dc.identifier.citationMOLECULES AND CELLS, v.41, no.12, pp.993 - 999-
dc.identifier.issn1016-8478-
dc.identifier.urihttp://hdl.handle.net/10203/250138-
dc.description.abstractOne of the most interesting findings from genome-wide expression analysis is that a considerable amount of noncoding RNA (ncRNA) is present in the cell. Recent studies have identified diverse biological functions of ncRNAs, which are expressed in a much wider array of forms than proteins. Certain ncRNAs associated with diseases, in particular, have attracted research attention as novel therapeutic targets and diagnostic markers. BC200 RNA, a 200-nucleotide ncRNA originally identified as a neuron-specific transcript, is abnormally overexpressed in several types of cancer tissue. A number of recent studies have suggested mechanisms by which abnormal expression of BC200 RNA contributes to the development of cancer. In this article, we first provide a brief review of a recent progress in identifying functions of BC200 RNA in cancer cells, and then offer examples of other ncRNAs as new therapeutic targets and diagnostic markers for human cancer. Finally, we discuss future directions of studies on BC200 RNA for new cancer treatments.-
dc.languageEnglish-
dc.publisherKOREAN SOC MOLECULAR & CELLULAR BIOLOGY-
dc.titleBC200 RNA: An Emerging Therapeutic Target and Diagnostic Marker for Human Cancer-
dc.typeArticle-
dc.identifier.wosid000454506000001-
dc.identifier.scopusid2-s2.0-85059245237-
dc.type.rimsART-
dc.citation.volume41-
dc.citation.issue12-
dc.citation.beginningpage993-
dc.citation.endingpage999-
dc.citation.publicationnameMOLECULES AND CELLS-
dc.identifier.doi10.14348/molcells.2018.0425-
dc.contributor.localauthorLee, Younghoon-
dc.contributor.nonIdAuthorKim, Meehyein-
dc.description.isOpenAccessN-
dc.type.journalArticleReview-
dc.subject.keywordAuthorBC200 RNA-
dc.subject.keywordAuthorcancer-
dc.subject.keywordAuthordiagnostic marker-
dc.subject.keywordAuthorncRNA (noncoding RNA)-
dc.subject.keywordAuthortherapeutic target-
dc.subject.keywordPlusLONG NONCODING RNA-
dc.subject.keywordPlusMICRORNA EXPRESSION-
dc.subject.keywordPlusEPIGENETIC REGULATION-
dc.subject.keywordPlusPOLY(A)-BINDING PROTEIN-
dc.subject.keywordPlusTRANSLATIONAL CONTROL-
dc.subject.keywordPlusCIRCULATING MIRNAS-
dc.subject.keywordPlusPOOR-PROGNOSIS-
dc.subject.keywordPlusBC1 RNA-
dc.subject.keywordPlusHOTAIR-
dc.subject.keywordPlusPLASTICITY-
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