Synergistic Ensemble of Optogenetic Actuators and Dynamic Indicators in Cell Biology

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dc.contributor.authorKim, Jihoonko
dc.contributor.authorHeo, Won Doko
dc.date.accessioned2018-11-22T06:43:07Z-
dc.date.available2018-11-22T06:43:07Z-
dc.date.created2018-11-13-
dc.date.created2018-11-13-
dc.date.issued2018-09-
dc.identifier.citationMOLECULES AND CELLS, v.41, no.9, pp.809 - 817-
dc.identifier.issn1016-8478-
dc.identifier.urihttp://hdl.handle.net/10203/246718-
dc.description.abstractDiscovery of the naturally evolved fluorescent proteins and their genetically engineered biosensors have enormously contributed to current bio-imaging techniques. These reporters to trace dynamic changes of intracellular protein activities have continuously transformed according to the various demands in biological studies. Along with that, light-inducible optogenetic technologies have offered scientists to perturb, control and analyze the function of intracellular machineries in spatio-temporal manner. In this review, we present an overview of the molecular strategies that have been exploited for producing genetically encoded protein reporters and various optogenetic modules. Finally, in particular, we discuss the current efforts for combined use of these reporters and optogenetic modules as a powerful tactic for the control and imaging of signaling events in cells and tissues.-
dc.languageEnglish-
dc.publisherKOREAN SOC MOLECULAR & CELLULAR BIOLOGY-
dc.subjectRED FLUORESCENT PROTEIN-
dc.subjectLIVING CELLS-
dc.subjectIN-VIVO-
dc.subjectFRET BIOSENSORS-
dc.subjectOPTICAL CONTROL-
dc.subjectSPATIOTEMPORAL REGULATION-
dc.subjectCOMPLEMENTATION SYSTEM-
dc.subjectMONOMERIC RED-
dc.subjectBLUE-LIGHT-
dc.subjectGREEN-
dc.titleSynergistic Ensemble of Optogenetic Actuators and Dynamic Indicators in Cell Biology-
dc.typeArticle-
dc.identifier.wosid000448310000001-
dc.type.rimsART-
dc.citation.volume41-
dc.citation.issue9-
dc.citation.beginningpage809-
dc.citation.endingpage817-
dc.citation.publicationnameMOLECULES AND CELLS-
dc.identifier.doi10.14348/molcells.2018.0295-
dc.contributor.localauthorHeo, Won Do-
dc.contributor.nonIdAuthorKim, Jihoon-
dc.description.isOpenAccessN-
dc.type.journalArticleReview-
dc.subject.keywordAuthorbiosensor-
dc.subject.keywordAuthoroptogenetics-
dc.subject.keywordPlusRED FLUORESCENT PROTEIN-
dc.subject.keywordPlusLIVING CELLS-
dc.subject.keywordPlusIN-VIVO-
dc.subject.keywordPlusFRET BIOSENSORS-
dc.subject.keywordPlusOPTICAL CONTROL-
dc.subject.keywordPlusSPATIOTEMPORAL REGULATION-
dc.subject.keywordPlusCOMPLEMENTATION SYSTEM-
dc.subject.keywordPlusMONOMERIC RED-
dc.subject.keywordPlusBLUE-LIGHT-
dc.subject.keywordPlusGREEN-
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