Synthesis and Biological Activity of Tetrameric Ribitol Phosphate Fragments of Staphylococcus aureus Wall Teichoic Acid
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Jung, Yoon Chul | ko |
| dc.contributor.author | Lee, Jaehyeok | ko |
| dc.contributor.author | Kim, Sang Ah | ko |
| dc.contributor.author | Schmidt, Timo | ko |
| dc.contributor.author | Lee, Wonchul | ko |
| dc.contributor.author | Lee, Bok Luel | ko |
| dc.contributor.author | Lee, Hee-Seung | ko |
| dc.date.accessioned | 2018-09-18T06:23:58Z | - |
| dc.date.available | 2018-09-18T06:23:58Z | - |
| dc.date.created | 2018-09-04 | - |
| dc.date.created | 2018-09-04 | - |
| dc.date.created | 2018-09-04 | - |
| dc.date.issued | 2018-08 | - |
| dc.identifier.citation | ORGANIC LETTERS, v.20, no.15, pp.4449 - 4452 | - |
| dc.identifier.issn | 1523-7060 | - |
| dc.identifier.uri | http://hdl.handle.net/10203/245571 | - |
| dc.description.abstract | A systematically designed and synthesized ribitol phosphate (RboP) oligomer using a series of building blocks, which make up the wall teichoic acid (WTA) of S. aureus, is presented. Based on the use of a solution-phase phosphodiester synthesis, a library of ribitol phosphate tetramers, decorated with D-alanine and N-acetylglucosamine (GlcNAc), were generated. The synthesized RboP tetramers showed increased cytokine levels in mice in a subcutaneous air pouch model. | - |
| dc.language | English | - |
| dc.publisher | AMER CHEMICAL SOC | - |
| dc.title | Synthesis and Biological Activity of Tetrameric Ribitol Phosphate Fragments of Staphylococcus aureus Wall Teichoic Acid | - |
| dc.type | Article | - |
| dc.identifier.wosid | 000441112700013 | - |
| dc.identifier.scopusid | 2-s2.0-85050944039 | - |
| dc.type.rims | ART | - |
| dc.citation.volume | 20 | - |
| dc.citation.issue | 15 | - |
| dc.citation.beginningpage | 4449 | - |
| dc.citation.endingpage | 4452 | - |
| dc.citation.publicationname | ORGANIC LETTERS | - |
| dc.identifier.doi | 10.1021/acs.orglett.8b01725 | - |
| dc.contributor.localauthor | Lee, Hee-Seung | - |
| dc.contributor.nonIdAuthor | Schmidt, Timo | - |
| dc.contributor.nonIdAuthor | Lee, Bok Luel | - |
| dc.description.isOpenAccess | N | - |
| dc.type.journalArticle | Article | - |
| dc.subject.keywordPlus | GRAM-POSITIVE BACTERIA | - |
| dc.subject.keywordPlus | LIPOTEICHOIC ACID | - |
| dc.subject.keywordPlus | ENTEROCOCCUS-FAECIUM | - |
| dc.subject.keywordPlus | INFECTIONS | - |
| dc.subject.keywordPlus | VACCINE | - |
| dc.subject.keywordPlus | COMPLEMENT | - |
| dc.subject.keywordPlus | RESISTANCE | - |
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