Water-soluble polypeptides comprised of repeat modules, method for preparing the same and method for a target-specific polypeptide and analysis of biological activity thereof인터날린 단백질의 N-말단 및 LRR 패밀리 단백질이 융합된 수용성 융합 폴리펩타이드 및 이의 제조 방법

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dc.contributor.author김학성ko
dc.contributor.author김동섭ko
dc.contributor.author이상철ko
dc.contributor.author이병철ko
dc.contributor.author한지은ko
dc.contributor.author이중재ko
dc.contributor.author박근완ko
dc.contributor.author홍승표ko
dc.date.accessioned2017-12-20T02:14:47Z-
dc.date.available2017-12-20T02:14:47Z-
dc.date.issued2016-09-13-
dc.identifier.urihttp://hdl.handle.net/10203/230443-
dc.description.abstractThe present invention relates to a soluble polypeptide comprised of repeat modules. More particularly, the present invention relates to a soluble fusion polypeptide of the N-terminal domain of internalin and LRR (Leucine rich repeat) family protein, a method for preparing the polypeptide, a vector comprising a nucleic acid sequence encoding the polypeptide, a host cell comprising the vector, a method for producing a solubility and folding-improved fusion polypeptide by expressing the vector in the host cell, and a method for improving the solubility and folding of the fusion polypeptide. Further, the present invention relates to a method for preparing the polypeptide bound with a specific target and analyzing the efficacy of the soluble polypeptide.-
dc.titleWater-soluble polypeptides comprised of repeat modules, method for preparing the same and method for a target-specific polypeptide and analysis of biological activity thereof-
dc.title.alternative인터날린 단백질의 N-말단 및 LRR 패밀리 단백질이 융합된 수용성 융합 폴리펩타이드 및 이의 제조 방법-
dc.typePatent-
dc.type.rimsPAT-
dc.contributor.localauthor김학성-
dc.contributor.localauthor김동섭-
dc.contributor.nonIdAuthor이상철-
dc.contributor.nonIdAuthor이병철-
dc.contributor.nonIdAuthor한지은-
dc.contributor.nonIdAuthor이중재-
dc.contributor.nonIdAuthor박근완-
dc.contributor.nonIdAuthor홍승표-
dc.contributor.assigneeKAIST-
dc.identifier.iprsType특허-
dc.identifier.patentApplicationNumber14005536-
dc.identifier.patentRegistrationNumber9441017-
dc.date.application2012-03-22-
dc.date.registration2016-09-13-
dc.publisher.countryUS-
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BS-Patent(특허)BiS-Patent(특허)
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