DSpace at KOASAS
College of Natural Sciences(자연과학대학)Dept. of Physics(물리학과)PH-Journal Papers(저널논문)

Measurements of Morphological and Biophysical Alterations in Individual Neuron Cells Associated with Early Neurotoxic Effects in Parkinson's Disease

Cited 56 time in webofscience Cited 0 time in scopus
  • Hit : 378
  • Download : 0
Export
DC FieldValueLanguage
dc.contributor.authorYang, Su-Ako
dc.contributor.authorYoon, Jongheeko
dc.contributor.authorKim, Kyoohyunko
dc.contributor.authorPark, YongKeunko
dc.date.accessioned2017-06-16T03:58:43Z-
dc.date.available2017-06-16T03:58:43Z-
dc.date.created2017-06-12-
dc.date.created2017-06-12-
dc.date.created2017-06-12-
dc.date.created2017-06-12-
dc.date.issued2017-05-
dc.identifier.citationCYTOMETRY PART A, v.91, no.5, pp.510 - 518-
dc.identifier.issn1552-4922-
dc.identifier.urihttp://hdl.handle.net/10203/224067-
dc.description.abstractParkinson's disease (PD) is a common neurodegenerative disease. However, therapeutic methods of PD are still limited due to complex pathophysiology in PD. Here, optical measurements of individual neurons from in vitro PD model using optical diffraction tomography (ODT) are presented. By measuring 3D refractive index distribution of neurons, morphological and biophysical alterations in in-vitro PD model are quantitatively investigated. It was found that neurons show apoptotic features in early PD progression. The present approach will open up new opportunities for quantitative investigation of the pathophysiology of various neurodegenerative diseases. (C) 2017 International Society for Advancement of Cytometry-
dc.languageEnglish-
dc.publisherWILEY-BLACKWELL-
dc.titleMeasurements of Morphological and Biophysical Alterations in Individual Neuron Cells Associated with Early Neurotoxic Effects in Parkinson's Disease-
dc.typeArticle-
dc.identifier.wosid000401842700012-
dc.identifier.scopusid2-s2.0-85018641960-
dc.type.rimsART-
dc.citation.volume91-
dc.citation.issue5-
dc.citation.beginningpage510-
dc.citation.endingpage518-
dc.citation.publicationnameCYTOMETRY PART A-
dc.identifier.doi10.1002/cyto.a.23110-
dc.contributor.localauthorPark, YongKeun-
dc.contributor.nonIdAuthorYang, Su-A-
dc.contributor.nonIdAuthorYoon, Jonghee-
dc.description.isOpenAccessN-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorParkinson&apos-
dc.subject.keywordAuthors disease-
dc.subject.keywordAuthorquantitative phase imaging-
dc.subject.keywordAuthor3D refractive index tomography-
dc.subject.keywordAuthorcell death-
dc.subject.keywordAuthorlabel-free-
dc.subject.keywordPlusOPTICAL DIFFRACTION TOMOGRAPHY-
dc.subject.keywordPlusSH-SY5Y NEUROBLASTOMA-CELLS-
dc.subject.keywordPlusLABEL-FREE CHARACTERIZATION-
dc.subject.keywordPlusTRANSFORM LIGHT-SCATTERING-
dc.subject.keywordPlusQUANTITATIVE PHASE-
dc.subject.keywordPlusDOPAMINERGIC-NEURONS-
dc.subject.keywordPlusOXIDATIVE STRESS-
dc.subject.keywordPlusINDUCED APOPTOSIS-
dc.subject.keywordPlusBLOOD-CELLS-
dc.subject.keywordPlusLIVE CELLS-
Appears in Collection
PH-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 56 items in WoS Click to see citing articles in records_button

Display Simple Item Record

qr_code

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


rss_1.0 rss_2.0 atom_1.0