This paper proposes a systematic risk evaluation framework for one of the most significant impact events on an interim dry storage facility, an aircraft crash, by using a probabilistic approach. A realistic case study that includes a specific cask model and selected impact conditions is performed to demonstrate the practical applicability of the proposed framework. An event tree analysis of an occurred aircraft crash that defines a set of impact conditions and storage cask response is constructed. The Monte-Carlo simulation is employed for the probabilistic approach in consideration of sources of uncertainty associated with the impact loads onto the internal storage casks. The parameters for representing uncertainties that are managed probabilistically include the aircraft impact velocity, the compressive strength of the reinforced concrete wall, the missile shape factor, and the facility wall thickness. Failure probabilities of the impacted wall and a single storage cask under direct mechanical impact load caused by the aircraft crash are estimated. A finite element analysis is applied to simulate the postulated direct engine impact load onto the cask body, and a source term analysis for associated releases of radioactive materials as well as an off-site consequence analysis are performed. Finally, conditional risk contribution calculations are represented by an event tree model. Case study results indicate that no severe risk is presented, as the radiological consequences do not exceed regulatory exposure limits to the public. This risk model can be used with any other representative detailed parameters and reference design concepts for other comparable direct or indirect impact conditions onto the cask body, which may provide an efficient way to investigate storage facility capacity to withstand an aircraft crash and thereby protect public health. (C) 2016 Elsevier B.V. All rights reserved.