Nanoindentation experiments and simulations are carried out to estimate the elastic modulus of freely-suspended-multilayer graphene. However, due to the difficulty of clamping all layers of multilayer graphene in experiments, and to the ambiguity of imposing the clamped boundary conditions in numerical simulations, the estimated values of elastic modulus exhibit large variation. In particular, interlayer sliding can affect the estimation of elastic modulus. From a series of molecular dynamics simulations, we demonstrate that the estimated elastic modulus of multilayer graphene depends on the level of interlayer sliding involved in boundary conditions. Under fully clamped boundary conditions that prevent interlayer sliding, the elastic modulus is constant regardless of the number of layers. In contrast, under weakly clamped boundary conditions that involve interlayer sliding, the elastic modulus decreases with increasing number of layers. In the case of weakly clamped conditions, a few wrinkles form in the interlayer and then coalesce into a single large wrinkle due to interlayer sliding. Our findings provide an understanding of the variation of elastic modulus observed in other experimental and numerical studies. Copyright (C) EPLA, 201