Quantitative trait loci mapping for fatty acid contents in the backfat on porcine chromosomes 1, 13, and 18

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A partial genome scan using microsatellite markers was conducted in order to detect quantitative trait loci (QTLs) for 10 fatty acid contents of the backfat in a pig reference population. Two QTLs were found by studying SSC1, SSC13, and SSC18, where QTLs had already been identified for backfat thickness. A QTL was located between marker loci S0113 and SW974 on chromosome 1; this QTL was only significantly detected (P < 0.05) for linoleic acid. The other QTL was discovered between markers S0062 and S0120 on chromosome 18, and its significance only showed (P < 0.05) for myristic acid. The two QTLs mapped to the same location as the backfat thickness QTL. A third of the phenotypic variation was explained for linoleic acid by the QTL on chromosome 1, and a quarter for myristic acid by the QTL on chromosome 18. Further studies on fine mapping and positional comparative candidate gene analyses will be the next step toward a better understanding of the genetic architecture of fatty acid contents.
Publisher
SPRINGER-VERLAG SINGAPORE PTE LTD
Issue Date
2003-02
Language
English
Article Type
Article
Keywords

INTRAMUSCULAR FAT; LINKAGE ANALYSIS; PIGS; GROWTH; THICKNESS; FATNESS; MUSCLE; GENES; QTL; LOCALIZATION

Citation

MOLECULES AND CELLS, v.15, no.1, pp.62 - 67

ISSN
1016-8478
URI
http://hdl.handle.net/10203/212965
Appears in Collection
MA-Journal Papers(저널논문)
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