DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Minsu | ko |
dc.contributor.author | Ha, Hyun Dong | ko |
dc.contributor.author | Kim, Yong-Tae | ko |
dc.contributor.author | Jung, Jae Hwan | ko |
dc.contributor.author | Kim, Shin-Hyun | ko |
dc.contributor.author | Kim, Do Hyun | ko |
dc.contributor.author | Seo, Tae Seok | ko |
dc.date.accessioned | 2016-04-20T06:14:23Z | - |
dc.date.available | 2016-04-20T06:14:23Z | - |
dc.date.created | 2015-11-24 | - |
dc.date.created | 2015-11-24 | - |
dc.date.created | 2015-11-24 | - |
dc.date.created | 2015-11-24 | - |
dc.date.issued | 2015-11 | - |
dc.identifier.citation | ANALYTICAL CHEMISTRY, v.87, no.21, pp.10969 - 10975 | - |
dc.identifier.issn | 0003-2700 | - |
dc.identifier.uri | http://hdl.handle.net/10203/205192 | - |
dc.description.abstract | A novel trace lead ion (Pb2+) detection platform by combining a microfluidic sample pretreatment device with a DNA aptamer linked photoluminescent graphene oxide quantum dot (GOQD) sensor was proposed. The multilayered microdevice included a microchamber which was packed with cation exchange resins for preconcentrating metal ions. The sample loading and recovery were automatically actuated by a peristaltic polydimethylsiloxane micropump with a flow rate of 84 mu L/min. Effects of the micropump actuation time, metal ion concentration, pH, and the volumes of the sample and eluent on the metal ion capture and preconcentration efficiency were investigated on a chip. The Pb2+ samples whose concentrations ranged from 0.48 nM to 1.2 mu M were successfully recovered with a preconcentration factor value between 4 and 5. Then, the preconcentrated metal ions were quantitatively analyzed with a DNA aptamer modified GOQD. The DNA aptamer on the GOQD specifically captured the target Pb2+ which can induce electron transfer from GOQD to Pb2+ upon UV irradiation, thereby resulting in the fluorescence quenching of the GOQD. The disturbing effect of foreign anions on the Pb2+ detection and the spiked Pb2+ real samples were also analyzed. The proposed GOQD metal ion sensor exhibited highly sensitive Pb2+ detection with a detection limit of 0.64 nM and a dynamic range from 1 to 1000 nM. The on-chip preconcentration of the trace metal ions from a large-volume sample followed by the metal ion detection by the fluorescent GOQD sensor can provide an advanced platform for on-site water pollution screening. | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Combination of a Sample Pretreatment Microfluidic Device with a Photoluminescent Graphene Oxide Quantum Dot Sensor for Trace Lead Detection | - |
dc.type | Article | - |
dc.identifier.wosid | 000364354900046 | - |
dc.identifier.scopusid | 2-s2.0-84946422934 | - |
dc.type.rims | ART | - |
dc.citation.volume | 87 | - |
dc.citation.issue | 21 | - |
dc.citation.beginningpage | 10969 | - |
dc.citation.endingpage | 10975 | - |
dc.citation.publicationname | ANALYTICAL CHEMISTRY | - |
dc.identifier.doi | 10.1021/acs.analchem.5b02907 | - |
dc.contributor.localauthor | Kim, Shin-Hyun | - |
dc.contributor.localauthor | Kim, Do Hyun | - |
dc.contributor.localauthor | Seo, Tae Seok | - |
dc.contributor.nonIdAuthor | Park, Minsu | - |
dc.contributor.nonIdAuthor | Ha, Hyun Dong | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | SOLID-PHASE EXTRACTION | - |
dc.subject.keywordPlus | ON FLUORESCENCE DETECTION | - |
dc.subject.keywordPlus | METAL-IONS | - |
dc.subject.keywordPlus | ENVIRONMENTAL-SAMPLES | - |
dc.subject.keywordPlus | AQUEOUS-SOLUTION | - |
dc.subject.keywordPlus | HIGH SELECTIVITY | - |
dc.subject.keywordPlus | MICRO-COLUMN | - |
dc.subject.keywordPlus | G-QUADRUPLEX | - |
dc.subject.keywordPlus | PRECONCENTRATION | - |
dc.subject.keywordPlus | PB2+ | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.