Rh(III)-catalyzed 7-azaindole synthesis via C-H activation/annulative coupling of aminopyridines with alkynes

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An efficient Rh(III)-catalyzed 7-azaindole synthesis was developed via C-H activation/annulative coupling of aminopyridines with alkynes. The reaction was highly regioselective and tolerated various functional groups, permitting the construction of various 7-azaindoles.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2015
Language
English
Article Type
Article
Keywords

PALLADIUM-CATALYZED HETEROANNULATION; INDOLE SYNTHESIS; INTERNAL ALKYNES; BIOLOGICAL EVALUATION; VERSATILE SYNTHESIS; KINASE INHIBITORS; BOND FORMATION; N BOND; ACTIVATION; PYRIDINES

Citation

CHEMICAL COMMUNICATIONS, v.51, no.56, pp.11202 - 11205

ISSN
1359-7345
DOI
10.1039/c5cc03497c
URI
http://hdl.handle.net/10203/200812
Appears in Collection
CH-Journal Papers(저널논문)
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