DC Field | Value | Language |
---|---|---|
dc.contributor.author | Sambudi, Nonni Soraya | ko |
dc.contributor.author | Sathya Murthy, Madhavi | ko |
dc.contributor.author | Lee, Gyun-Min | ko |
dc.contributor.author | Park, Seung-Bin | ko |
dc.date.accessioned | 2015-04-07T05:03:35Z | - |
dc.date.available | 2015-04-07T05:03:35Z | - |
dc.date.created | 2014-12-16 | - |
dc.date.created | 2014-12-16 | - |
dc.date.issued | 2015-01 | - |
dc.identifier.citation | COMPOSITES SCIENCE AND TECHNOLOGY, v.106, pp.76 - 84 | - |
dc.identifier.issn | 0266-3538 | - |
dc.identifier.uri | http://hdl.handle.net/10203/195263 | - |
dc.description.abstract | The role of CaCO3 nanoparticles as a reinforcing agent in increasing the mechanical properties of electrospun chitosan/poly(vinyl alcohol) (PVA) is inspired by the incorporation of CaCO3 inside a chitin network in nature. The loading concentration of CaCO3 nanoparticles varied from 1 to 5 wt%, and the diameter of fibers ranges from 71.5 +/- 23.4 nm to 140.7 +/- 15.1 nm with an increased loading of CaCO3. A tensile test on 4 wt% CaCO3-reinforced fibers revealed a Young's modulus up to 912.5 +/- 60.6 MPa from 15.7 +/- 3 MPa, which is almost sixty times the value of fibers without CaCO3. The biocompatibilities of the CaCO3-loaded fibers were also tested in a 14-day simulated body fluid (SBF) incubation to induce the formation of apatite minerals and in a 14-day cell proliferation assay with ATDC5 cells. The chitosan/PVA-CaCO3 (4 wt%) was found to provide the most suitable environment for cell growth in comparison with chitosan/PVA and chitosan/PVA-apatite. The CaCO3-reinforced chitosan/PVA has potential to be a promising alternative as an artificial cartilage. (C) 2014 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.subject | GUIDED BONE REGENERATION | - |
dc.subject | COMPOSITES | - |
dc.subject | CHITOSAN | - |
dc.subject | HYDROXYAPATITE | - |
dc.subject | FIBERS | - |
dc.subject | NANOCOMPOSITES | - |
dc.subject | NANOFIBERS | - |
dc.subject | SCAFFOLDS | - |
dc.subject | CELLS | - |
dc.subject | BIOMATERIALS | - |
dc.title | Electrospun chitosan/poly(vinyl alcohol) reinforced with CaCO3 nanoparticles with enhanced mechanical properties and biocompatibility for cartilage tissue engineering | - |
dc.type | Article | - |
dc.identifier.wosid | 000347868200007 | - |
dc.identifier.scopusid | 2-s2.0-84911876810 | - |
dc.type.rims | ART | - |
dc.citation.volume | 106 | - |
dc.citation.beginningpage | 76 | - |
dc.citation.endingpage | 84 | - |
dc.citation.publicationname | COMPOSITES SCIENCE AND TECHNOLOGY | - |
dc.identifier.doi | 10.1016/j.compscitech.2014.11.003 | - |
dc.contributor.localauthor | Lee, Gyun-Min | - |
dc.contributor.localauthor | Park, Seung-Bin | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Nano particles | - |
dc.subject.keywordAuthor | Particle-reinforced composites | - |
dc.subject.keywordAuthor | Mechanical properties | - |
dc.subject.keywordAuthor | Electro-spinning | - |
dc.subject.keywordPlus | GUIDED BONE REGENERATION | - |
dc.subject.keywordPlus | COMPOSITES | - |
dc.subject.keywordPlus | CHITOSAN | - |
dc.subject.keywordPlus | HYDROXYAPATITE | - |
dc.subject.keywordPlus | FIBERS | - |
dc.subject.keywordPlus | NANOCOMPOSITES | - |
dc.subject.keywordPlus | NANOFIBERS | - |
dc.subject.keywordPlus | SCAFFOLDS | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | BIOMATERIALS | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.