Photo- and pH-Tunable Multicolor Fluorescent Nanoparticle-Based Spiropyran-and BODIPY-Conjugated Polymer with Graphene Oxide

Cited 37 time in webofscience Cited 0 time in scopus
  • Hit : 100
  • Download : 0
We report a stimuli-responsive fluorescent nanomaterial, based on graphene oxide coupled with a polymer conjugated with photochromic spiropyran (SP) dye and hydrophobic boron dipyrromethane (BODIPY) dye, for application in triggered target multicolor bioimaging. Graphene oxide (GO) was reduced by catechol-conjugated polymers under mildly alkaline conditions, which enabled to formation of functionalized multicolor graphene nanoparticles that can be induced by irradiation with UV light and by changing the pH from acidic to neutral. Investigation of these nanoparticles by using AFM, fluorescence emission, and in vitro cell and in vivo imaging revealed that they show different tunable colors in bioimaging applications and, more specifically, in cancer-cell detection. The stability, biocompatibility, and quenching efficacy of this nanocomposite open a different perspective for cell imaging in different independent colors, sequentially and simultaneously.
Publisher
WILEY-V C H VERLAG GMBH
Issue Date
2014-10
Language
English
Article Type
Article
Keywords

DRUG-DELIVERY; RESPONSIVE POLYMERS; DERIVATIVES; EFFICIENT; THERAPY; SURFACE; PROBES; DYES

Citation

CHEMISTRY-AN ASIAN JOURNAL, v.9, no.10, pp.2921 - 2927

ISSN
1861-4728
DOI
10.1002/asia.201402399
URI
http://hdl.handle.net/10203/194495
Appears in Collection
CH-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 37 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0