Electrochemical Immunosensing Chip Using Selective Surface Modification, Capillary-Driven Microfluidic Control, and Signal Amplification by Redox Cycling

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dc.contributor.authorKim, Byung-Kwonko
dc.contributor.authorYang, Sang-Younko
dc.contributor.authorAziz, Md. Abdulko
dc.contributor.authorJo, Kyungminko
dc.contributor.authorSung, Daekyungko
dc.contributor.authorJon, Sangyongko
dc.contributor.authorWoo, Han Youngko
dc.contributor.authorYang, Haesikko
dc.date.accessioned2014-12-09T01:28:28Z-
dc.date.available2014-12-09T01:28:28Z-
dc.date.created2014-08-29-
dc.date.created2014-08-29-
dc.date.issued2010-10-
dc.identifier.citationELECTROANALYSIS, v.22, no.19, pp.2235 - 2244-
dc.identifier.issn1040-0397-
dc.identifier.urihttp://hdl.handle.net/10203/192399-
dc.description.abstractA sensitive electrochemical immunosensing chip is presented by employing (i) selective modification of protein-resistant surfaces; (ii) fabrication of a stable Ag/AgCl reference electrode; (iii) capillary-driven microfluidic control; (iv) signal amplification by redox cycling along with enzymatic reaction. Purely capillary-driven microfluidic control is combined with electrochemical sandwich-type immunosensing procedure. Selective modification of the surfaces is achieved by chemical reactivity-controlled patterning and electrochemical deposition. Fluidic control of the immunosensing chip is achieved by spontaneous capillary-driven flows and passive washing. The detection limit for mouse IgG in the immunosensing chip is 10 pg/mL.-
dc.languageEnglish-
dc.publisherWILEY-V C H VERLAG GMBH-
dc.subjectTIN OXIDE ELECTRODE-
dc.subjectGLUCOSE SENSOR-
dc.subjectAVIDIN-BINDING-
dc.subjectELECTROPHORESIS-
dc.subjectDEVICES-
dc.subjectFLOW-
dc.subjectPOLY(DIMETHYLSILOXANE)-
dc.subjectNANOPARTICLES-
dc.subjectBIOSENSORS-
dc.subjectSTABILITY-
dc.titleElectrochemical Immunosensing Chip Using Selective Surface Modification, Capillary-Driven Microfluidic Control, and Signal Amplification by Redox Cycling-
dc.typeArticle-
dc.identifier.wosid000283275100014-
dc.type.rimsART-
dc.citation.volume22-
dc.citation.issue19-
dc.citation.beginningpage2235-
dc.citation.endingpage2244-
dc.citation.publicationnameELECTROANALYSIS-
dc.contributor.localauthorJon, Sangyong-
dc.contributor.nonIdAuthorKim, Byung-Kwon-
dc.contributor.nonIdAuthorYang, Sang-Youn-
dc.contributor.nonIdAuthorAziz, Md. Abdul-
dc.contributor.nonIdAuthorJo, Kyungmin-
dc.contributor.nonIdAuthorSung, Daekyung-
dc.contributor.nonIdAuthorWoo, Han Young-
dc.contributor.nonIdAuthorYang, Haesik-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorImmunosensor-
dc.subject.keywordAuthorPassive washing-
dc.subject.keywordAuthorMicrofluidic control-
dc.subject.keywordAuthorNonspecific binding-
dc.subject.keywordAuthorAg/AgCl reference electrode-
dc.subject.keywordPlusTIN OXIDE ELECTRODE-
dc.subject.keywordPlusGLUCOSE SENSOR-
dc.subject.keywordPlusAVIDIN-BINDING-
dc.subject.keywordPlusELECTROPHORESIS-
dc.subject.keywordPlusDEVICES-
dc.subject.keywordPlusFLOW-
dc.subject.keywordPlusPOLY(DIMETHYLSILOXANE)-
dc.subject.keywordPlusNANOPARTICLES-
dc.subject.keywordPlusBIOSENSORS-
dc.subject.keywordPlusSTABILITY-
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