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Kim, Hail (김하일)
교수, (의과학대학원)

https://imodkaist.wixsite.com/home

Research Area
gene expression biochemistry, endocrinology, molecular genetics
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    NO Title, Author(s) (Publication Title, Volume Issue, Page, Issue Date)
    1
    Multiparity increases the risk of diabetes by impairing the proliferative capacity of pancreatic β cells

    Moon, Joon Ho; Lee, Joonyub; Kim, Kyun Hoo; et al, EXPERIMENTAL AND MOLECULAR MEDICINE, v.55, no.10, pp.2269 - 2280, 2023-10

    2
    Synthesis and biological evaluation of xanthine derivatives with phenacyl group as tryptophan hydroxylase 1 (TPH1) inhibitors for obesity and fatty liver disease

    Yoon, Jihyeon; Choi, Won-Il; Parameswaran, Saravanan; et al, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.94, 2023-10

    3
    Arginine 65 methylation of Neurogenin 3 by PRMT1 is required for pancreatic endocrine development of hESCs

    Cho, Gahyang; Hyun, Kwangbeom; Choi, Jieun; et al, EXPERIMENTAL AND MOLECULAR MEDICINE, v.55, no.7, pp.1506 - 1519, 2023-07

    4
    Tcf7l2 in hepatocytes regulates de novo lipogenesis in diet-induced non-alcoholic fatty liver disease in mice

    Lee, Da Som; An, Tae Hyeon; Kim, Hyunmi; et al, DIABETOLOGIA, v.66, no.5, pp.931 - 954, 2023-05

    5
    Serotonin in the regulation of systemic energy metabolism

    Moon, Joon Ho; Oh, Chang-Myung; Kim, Hail, JOURNAL OF DIABETES INVESTIGATION, v.13, no.10, pp.1639 - 1645, 2022-10

    6
    Synthesis and biological evaluation of tyrosine derivatives as peripheral 5HT(2A) receptor antagonists for nonalcoholic fatty liver disease

    Kim, Minhee; Choi, Wonil; Yoon, Jihyeon; et al, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.239, 2022-09

    7
    Mitoribosome insufficiency in beta cells is associated with type 2 diabetes-like islet failure

    Hong, Hyun Jung; Joung, Kyong Hye; Kim, Yong Kyung; et al, EXPERIMENTAL AND MOLECULAR MEDICINE, v.54, no.7, pp.932 - 945, 2022-07

    8
    Identification of New Non-BBB Permeable Tryptophan Hydroxylase Inhibitors for Treating Obesity and Fatty Liver Disease

    Pagire, Suvarna H.; Pagire, Haushabhau S.; Park, Kun-Young; et al, MOLECULES, v.27, no.11, 2022-06

    9
    Lysosomal Ca2+-mediated TFEB activation modulates mitophagy and functional adaptation of pancreatic beta-cells to metabolic stress

    Park, Kihyoun; Lim, Hyejin; Kim, Jinyoung; et al, NATURE COMMUNICATIONS, v.13, no.1, 2022-03

    10
    Ribes fasciculatum Ameliorates High-Fat-Diet-Induced Obesity by Elevating Peripheral Thermogenic Signaling

    Lee, Yuna; Park, Yeo-Jin; Lee, Bonggi; et al, MOLECULES, v.27, no.5, 2022-03

    11
    Serotonergic Regulation of Hepatic Energy Metabolism

    Park, Jiwon; Jeong, Wooju; Yun, Chahyeon; et al, ENDOCRINOLOGY AND METABOLISM, v.36, no.6, pp.1151 - 1160, 2021-12

    12
    Inhibiting serotonin signaling through HTR2B in visceral adipose tissue improves obesity-related insulin resistance

    Choi, Won Gun; Choi, Wonsuk; Oh, Tae Jung; et al, JOURNAL OF CLINICAL INVESTIGATION, v.131, no.23, 2021-12

    13
    Protein Arginine Methyltransferase 1 Is Essential for the Meiosis of Male Germ Cells

    Waseem, Sahar; Kumar, Sudeep; Lee, Kanghoon; et al, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.22, no.15, 2021-08

    14
    Proto-oncoprotein Zbtb7c and SIRT1 repression: implications in high-fat diet-induced and age-dependent obesity

    Choi, Won-Il; Yoon, Jae-Hyun; Choi, Seo-Hyun; et al, EXPERIMENTAL AND MOLECULAR MEDICINE, v.53, no.5, pp.917 - 932, 2021-05

    15
    A Systems Biology Approach to Investigating the Interaction between Serotonin Synthesis by Tryptophan Hydroxylase and the Metabolic Homeostasis

    Park, Suhyeon; Kim, Yumin; Lee, Jibeom; et al, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.22, no.5, 2021-03

    16
    Differential roles of GDF15 and FGF21 in systemic metabolic adaptation to the mitochondrial integrated stress response

    Kang, Seul Gi; Choi, Min Jeong; Jung, Saet-Byel; et al, ISCIENCE, v.24, no.3, 2021-03

    17
    Peripheral Selective Oxadiazolylphenyl Alanine Derivatives as Tryptophan Hydroxylase 1 Inhibitors for Obesity and Fatty Liver Disease

    Bae, Eun Jung; Choi, Won Gun; Pagire, Haushabhau S.; et al, JOURNAL OF MEDICINAL CHEMISTRY, v.64, no.2, pp.1037 - 1053, 2021-01

    18
    YAP and AP-1 Cooperate to Initiate Pancreatic Cancer Development from Ductal Cells in Mice

    Park, Jaeoh; Eisenbarth, David; Choi, Wonyoung; et al, CANCER RESEARCH, v.80, no.21, pp.4768 - 4779, 2020-11

    19
    Serotonin Regulates De Novo Lipogenesis in Adipose Tissues through Serotonin Receptor 2A

    Shong, Ko Eun; Oh, Chang-Myung; Namkung, Jun; et al, ENDOCRINOLOGY AND METABOLISM, v.35, no.2, pp.470 - 479, 2020-06

    20
    An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models

    Choi, Min Jeong; Jung, Saet-Byel; Lee, Seong Eun; et al, DIABETOLOGIA, v.63, no.4, pp.837 - 852, 2020-04
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