Researcher Page

사진

Lee, Gyun Min (이균민) C-2020-2011

Department
Department of Biological Sciences(생명과학과)
Website
http://bs.kaist.ac.kr/~acelab/HomePage
Research Area
Proteomics, Cell engineering, Bio-reactor (Fed-batch, Perfusion culture)

Keyword Cloud

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1

Mitigating Clonal Variation in Recombinant Mammalian Cell Lines

Lee, Jae Seong; Kildegaard, Helene Faustrup; Lewis, Nathan E.; et al, TRENDS IN BIOTECHNOLOGY, v.37, no.9, pp.931 - 942, 2019-09

2

Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference

Xiong, Kai; Marquart, Kim Fabiano; Karottki, Karen Julie la Cour; et al, BIOTECHNOLOGY AND BIOENGINEERING, v.116, no.7, pp.1813 - 1819, 2019-06

3

Analysis of Golgi pH in Chinese hamster ovary cells using ratiometric pH-sensitive fluorescent proteins

Lee, Jong Hyun; Kim, Jihoon; Park, Jong-Ho; et al, BIOTECHNOLOGY AND BIOENGINEERING, v.116, no.5, pp.1006 - 1016, 2019-05

4

Systematic Evaluation of Site-Specific Recombinant Gene Expression for Programmable Mammalian Cell Engineering

Pristovsek, Nusa; Nallapareddy, Saranya; Grav, Lise Marie; et al, ACS SYNTHETIC BIOLOGY, v.8, no.4, pp.758 - 774, 2019-04

5

Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles

Amann, Thomas; Hansen, Anders Holmgaard; Kol, Stefan; et al, METABOLIC ENGINEERING, v.52, pp.143 - 152, 2019-03

6

Improving recombinant bone morphogenetic protein-4 (BMP-4) production by autoregulatory feedback loop removal using BMP receptor-knockout CHO cell lines

Kim, Che Lin; Lee, Gyun Minresearcher, METABOLIC ENGINEERING, v.52, pp.57 - 67, 2019-03

7

Revealing Key Determinants of Clonal Variation in Transgene Expression in Recombinant CHO Cells Using Targeted Genome Editing

Jae Seong Lee; Park, Jin-Hyoung; Ha, Tae Kwang; et al, ACS SYNTHETIC BIOLOGY, v.7, no.12, pp.2867 - 2878, 2018-12

8

Improving the production of recombinant human bone morphogenetic protein-4 in Chinese hamster ovary cell cultures by inhibition of undesirable endocytosis

Kim, Che Lin; Jung, Mi Yeong; Kim, Young Sik; et al, BIOTECHNOLOGY AND BIOENGINEERING, v.115, no.10, pp.2565 - 2575, 2018-10

9

Differential expression of microRNAs in recombinant Chinese hamster ovary cells treated with sodium butyrate using digital RNA counting

Lim, Sung-Min; Park, Sun-Hye; Lee, Joohyoung; et al, JOURNAL OF BIOTECHNOLOGY, v.283, pp.37 - 42, 2018-10

10

CRISPR/Cas9-Multiplexed Editing of Chinese Hamster Ovary B4Gal-T1, 2, 3, and 4 Tailors N-Glycan Profiles of Therapeutics and Secreted Host Cell Proteins

Amann, Thomas; Hansen, Anders Holmgaard; Kol, Stefan; et al, BIOTECHNOLOGY JOURNAL, v.13, no.10, 2018-10

11

Minimizing Clonal Variation during Mammalian Cell Line Engineering for Improved Systems Biology Data Generation

Grav, Lise Marie; Sergeeva, Dania; Lee, Jae Seong; et al, ACS SYNTHETIC BIOLOGY, v.7, no.9, pp.2148 - 2159, 2018-09

12

Untangling the mechanism of 3-methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3-methyladenine

Baek, Eric H; Lee, Jae Seong; Lee, Gyun Minresearcher, BIOTECHNOLOGY AND BIOENGINEERING, v.115, no.9, pp.2243 - 2254, 2018-09

13

Simple and Robust N-Glycan Analysis Based on Improved 2-Aminobenzoic Acid Labeling for Recombinant Therapeutic Glycoproteins

Jeong, Yeong Ran; Kim, Sun Young; Park, Young Sam; et al, JOURNAL OF PHARMACEUTICAL SCIENCES, v.107, no.7, pp.1831 - 1841, 2018-07

14

Co-amplification of EBNA-1 and PyLT through dhfr-mediated gene amplification for improving foreign protein production in transient gene expression in CHO cells

Lee, Joohyoung; Park, Jong-Ho; Park, Sun-Hye; et al, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.102, no.11, pp.4729 - 4739, 2018-06

15

Glutamine synthetase gene knockout-human embryonic kidney 293E cells for stable production of monoclonal antibodies

Yu, Da Young; Lee, Sang Yoon; Lee, Gyun Minresearcher, BIOTECHNOLOGY AND BIOENGINEERING, v.115, no.5, pp.1367 - 1372, 2018-05

16

Comprehensive Physicochemical and Biological Characterization of the Proposed Biosimilar Darbepoetin Alfa, LBDE, and Its Originator Darbepoetin Alfa, NESPA (R)

Jeong, Yeong Ran; Jeong, Rae Ung; Son, Jeong Hyun; et al, BIODRUGS, v.32, no.2, pp.153 - 168, 2018-04

17

Comprehensive Physicochemical and Biological Characterization of the Proposed Biosimilar Darbepoetin-a, LBDE and Originator Darbepoetin-a, NESP®

Jeong, Yeong Ran; Jeong, Rae Ung; Son, Jeong Hyun; et al, BIODRUGS, v.32, no.2, pp.153 - 168, 2018-04

18

Baicalein Reduces Oxidative Stress in CHO Cell Cultures and Improves Recombinant Antibody Productivity

Ha, Tae Kwang; Hansen, Anders Holmgaard; Kol, Stefan; et al, Biotechnology Journal, v.13, no.3, 2018-03

19

Using Titer and Titer Normalized to Confluence Are Complementary Strategies for Obtaining Chinese Hamster Ovary Cell Lines with High Volumetric Productivity of Etanercept

Pristovsek, Nusa; Hansen, Henning Gram; Sergeeva, Daria; et al, BIOTECHNOLOGY JOURNAL, v.13, no.3, pp.1 - 10, 2018-03

20

Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies

Noh, Soo Min; Shin, Seunghyeon; Lee, Gyun Minresearcher, SCIENTIFIC REPORTS, v.8, no.5361, pp.1 - 11, 2018-03

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