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Lee, Gyun Min (이균민)
명예교수, (생명과학과)

https://sites.google.com/view/kaistacelab

Research Area
Proteomics, Cell engineering, Bio-reactor (Fed-batch, Perfusion culture)
Co-researchers
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    NO Title, Author(s) (Publication Title, Volume Issue, Page, Issue Date)
    1
    Extraction of the outer membrane protein pertactin from Bordetella pertussis with urea for the production of acellular pertussis vaccine

    Moon, JaeHoon; Park, Jong Kwan; Park, Bu Young; et al, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.29, no.3, pp.505 - 512, 2024-06

    2
    Enhancing the production of adeno-associated virus (AAV)2 and AAV9 with high full capsid ratio in HEK293 cells through design-of-experiment optimization of triple plasmid ratio

    Park, Sungje; Shin, Seunghyeon; Lee, Haeshin; et al, BIOTECHNOLOGY JOURNAL, v.19, no.3, 2024-03

    3
    Genome-wide CRISPR/Cas9 knockout screening to mitigate cell growth inhibition induced by histone deacetylase inhibitors in recombinant CHO cells

    Kim, Dongil; Kim, Su Hyun; Yoon, Chansik; et al, BIOTECHNOLOGY AND BIOENGINEERING, v.121, no.3, pp.931 - 941, 2024-03

    4
    Enhancing the production of recombinant human TGF-β1 through an understanding of TGF-β1 synthesis, signaling, and endocytosis in CHO cells

    Kim, Kyungsoo; Kim, Young Sik; Jang, Ju Woong; et al, BIOTECHNOLOGY JOURNAL, v.19, no.1, 2024-01

    5
    In vitro induction of in vivo -relevant stellate astrocytes in 3D brain-derive d, decellularize d extracellular matrices

    Han, Sol; Kim, Jungnam; Kim, Su Hyun; et al, ACTA BIOMATERIALIA, v.172, pp.218 - 233, 2023-12

    6
    Mitigating transcriptional bottleneck using a constitutively active transcription factor, VP16-CREB, in mammalian cells

    Yoon, Chansik; Baek, Kyoung Eun; Kim, Dongil; et al, METABOLIC ENGINEERING, v.80, pp.33 - 44, 2023-11

    7
    Identification of hyperosmotic stress-responsive genes in Chinese hamster ovary cells via genome-wide virus-free CRISPR/Cas9 screening

    Kim, Su Hyun; Shin, Seunghyeon; Baek, Minhye; et al, METABOLIC ENGINEERING, v.80, pp.66 - 77, 2023-11

    8
    Enhanced cell growth, production, and mAb quality produced in Chinese hamster ovary-K1 cells by supplementing polyamine in the media

    Kang, Da Eun; An, Yeong Bin; Kim, Yeunju; et al, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.107, no.9, pp.2855 - 2870, 2023-05

    9
    Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium

    Ha, Tae Kwang; Odena, Andreu; Karottki, Karen Julie la Cour; et al, BIOTECHNOLOGY AND BIOENGINEERING, v.120, no.4, pp.1159 - 1166, 2023-04

    10
    Improving bone morphogenetic protein (BMP) production in CHO cells through understanding of BMP synthesis, signaling and endocytosis

    Kim, Kyungsoo; Kim, Mi Gyeom; Lee, Gyun Min, BIOTECHNOLOGY ADVANCES, v.62, 2023-01

    11
    Recombinase-mediated cassette exchange-based screening of a CRISPR/Cas9 library for enhanced recombinant protein production in human embryonic kidney cells: Improving resistance to hyperosmotic stress

    Shin, Seunghyeon; Kim, Su Hyun; Park, Jong-Ho; et al, METABOLIC ENGINEERING, v.72, pp.247 - 258, 2022-07

    12
    Development of an in vitro screening system for synthetic signal peptide in mammalian cell-based protein production

    Park, Jong-Ho; Lee, Hoon-Min; Jin, Eun-Ju; et al, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.106, no.9-10, pp.3571 - 3582, 2022-05

    13
    Small molecule epigenetic modulators for enhancing recombinant antibody production in CHO cell cultures

    Kim, Dongil; Yoon, Chansik; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.119, no.3, pp.820 - 831, 2022-03

    14
    Improving the secretory capacity of CHO producer cells: The effect of controlled Blimp1 expression, a master transcription factor for plasma cells

    Kim, Su Hyun; Baek, Minhye; Park, Sungje; et al, METABOLIC ENGINEERING, v.69, pp.73 - 86, 2022-01

    15
    Factors affecting the quality of therapeutic proteins in recombinant Chinese hamster ovary cell culture

    Ha, Tae Kwang; Kim, Dongil; Kim, Che Lin; et al, BIOTECHNOLOGY ADVANCES, v.54, 2022-01

    16
    Blockage of undesirable endocytosis of recombinant human growth/differentiation factor-5 in Chinese hamster ovary cell cultures requires heparin analogs with specific chain lengths

    Kim, Mi Gyeom; Lee, Gyun Min, BIOTECHNOLOGY JOURNAL, v.16, no.10, pp.2100227, 2021-10

    17
    A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells

    Shamie, Isaac; Duttke, Sascha H.; Karottki, Karen J. la Cour; et al, NAR GENOMICS AND BIOINFORMATICS, v.3, no.3, 2021-09

    18
    An optimized genome-wide, virus-free CRISPR screen for mammalian cells

    Xiong, Kai; la Cour Karottki, Karen Julie; Hefzi, Hooman; et al, Cell Reports Methods, v.1, no.4, 2021-08

    19
    A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes

    Karottki, Karen Julie la Cour; Hefzi, Hooman; Li, Songyuan; et al, METABOLIC ENGINEERING, v.66, pp.114 - 122, 2021-07

    20
    Streamlined Human Cell-Based Recombinase-Mediated Cassette Exchange Platform Enables Multigene Expression for the Production of Therapeutic Proteins

    Shin, Seunghyeon; Kim, Su Hyun; Lee, Jae Seong; et al, ACS SYNTHETIC BIOLOGY, v.10, no.7, pp.1715 - 1727, 2021-07
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