Susceptibility Compensated fMRI Study Using a Tailored RF Echo Planar Imaging Sequence

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dc.contributor.authorChung, JYko
dc.contributor.authorYoon, HWko
dc.contributor.authorKim, YBko
dc.contributor.authorPark, HyunWookko
dc.contributor.authorCho, ZHko
dc.date.accessioned2009-06-29T06:37:01Z-
dc.date.available2009-06-29T06:37:01Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued2009-01-
dc.identifier.citationJOURNAL OF MAGNETIC RESONANCE IMAGING, v.29, pp.221 - 228-
dc.identifier.issn1053-1807-
dc.identifier.urihttp://hdl.handle.net/10203/9836-
dc.description.abstractPurpose: To implement a method using a tailored radiofrequency (TRF) pulse with a quadratic phase profile to recover susceptibility-induced signal losses in gradient-recalled echo-planar images (EPI). Materials and Methods: A functional magnetic resonance imaging (fMRI) experiment for compensation of susceptibility artifacts. known as the TRIF pulse EPI sequence (TRF-EPI), was used. TRF pulse compensates the susceptibility effect with a reduced signal-to-noise ratio (SNR) to one-half when the maximum phase distribution is 2 pi. We demonstrate theoretically that the maximum phase distribution can also be reduced to 7 rather than 2 pi. improving the SNR accordingly. An analysis was conducted comparing this newly proposed strategy using a standard RF excitation with a linear phase distribution and a quadratic TRF excitation with a pi phase distribution. Results: Thorough experimental comparisons were also made between the TRF quadratic excitation with a pi phase profile and conventional EPI with a standard excitation in human subjects during ventral brain activation. Conclusion: With reduced maximum phase distribution in the TRF pulse. signals in the susceptibility-affected areas, such as the orbitofrontal and interior temporal cortex. were increased. suggesting that the technique Could be a useful adjunct to fMRI.-
dc.description.sponsorshipMOST(Korean Ministry of Science and Tech-nology); Contract grant numbers; M10530010001-06N3001-00110 and M1053001002-06N3001-00210.en
dc.languageEnglish-
dc.language.isoen_USen
dc.publisherJOHN WILEY & SONS INC-
dc.subjectBOLD SENSITIVITY LOSSES-
dc.subjectINDUCED SIGNAL LOSS-
dc.subjectGRADIENT-ECHO-
dc.subjectFUNCTIONAL MRI-
dc.subjectORBITOFRONTAL CORTEX-
dc.subjectZ-SHIM-
dc.subjectFIELD INHOMOGENEITIES-
dc.subjectHUMAN BRAIN-
dc.subjectSPIN-ECHO-
dc.subjectARTIFACTS-
dc.titleSusceptibility Compensated fMRI Study Using a Tailored RF Echo Planar Imaging Sequence-
dc.typeArticle-
dc.identifier.wosid000262168200029-
dc.identifier.scopusid2-s2.0-60349110365-
dc.type.rimsART-
dc.citation.volume29-
dc.citation.beginningpage221-
dc.citation.endingpage228-
dc.citation.publicationnameJOURNAL OF MAGNETIC RESONANCE IMAGING-
dc.identifier.doi10.1002/jmri.21397-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.contributor.localauthorPark, HyunWook-
dc.contributor.nonIdAuthorChung, JY-
dc.contributor.nonIdAuthorYoon, HW-
dc.contributor.nonIdAuthorKim, YB-
dc.contributor.nonIdAuthorCho, ZH-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorsusceptibility-
dc.subject.keywordAuthorfMRI-
dc.subject.keywordAuthortailored RF (TRF)-
dc.subject.keywordAuthorsignal loss-
dc.subject.keywordAuthororbitofrontal cortex-
dc.subject.keywordAuthorinterior temporal cortex-
dc.subject.keywordPlusBOLD SENSITIVITY LOSSES-
dc.subject.keywordPlusINDUCED SIGNAL LOSS-
dc.subject.keywordPlusGRADIENT-ECHO-
dc.subject.keywordPlusFUNCTIONAL MRI-
dc.subject.keywordPlusORBITOFRONTAL CORTEX-
dc.subject.keywordPlusZ-SHIM-
dc.subject.keywordPlusFIELD INHOMOGENEITIES-
dc.subject.keywordPlusHUMAN BRAIN-
dc.subject.keywordPlusSPIN-ECHO-
dc.subject.keywordPlusARTIFACTS-
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