A More Comprehensive and Highly Practical Solution to Enantioselective Aldehyde Crotylation

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The enantioselective crotylation of aldehydes with 1,2-diaminochlorocrotylsilane reagents is effectively catalyzed by Sc(OTf)(3). The one significant limitation on the utility of these reagents - substrate scope - has thus been addressed. The net result is the most comprehensive and highly practical method for enantioselective aldehyde crotylation yet advanced.
Publisher
AMER CHEMICAL SOC
Issue Date
2011-05
Language
English
Article Type
Article
Citation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.133, no.17, pp.6517 - 6520

ISSN
0002-7863
DOI
10.1021/ja200712f
URI
http://hdl.handle.net/10203/96642
Appears in Collection
CH-Journal Papers(저널논문)
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