유체영동 기반의 입자분리현상을 이용한 세포 크기 측정방법 Microfluidic cell sizing using hydrophoretic size-based separation

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This paper presents a microfluidic cell sizing method using hydrophoretic size-based separation. By exploiting slanted obstacles in a microchannel, we can generate a lateral pressure gradient so that microparticles can be deflected and arranged along lateral flows induced by the gradient. Using such movement of particles, we discriminated 8 to 15 μm-sized beads. We measured the size of U937 cells by comparing the hydrophoretic response of the cells to those of the size-standard beads whose diameters are known. Due to its simple design and fabrication, the sizing method can be easily integrated with other microfluidic components such as cell culture chambers conducting on-chip sizing and sorting.
Publisher
한국센서학회
Issue Date
2008-07
Language
Korean
Citation

센서학회지, v.17, no.4, pp.245 - 249

ISSN
1225-5475
URI
http://hdl.handle.net/10203/89531
Appears in Collection
BiS-Journal Papers(저널논문)
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