Structure-activity relationship studies of the chromosome segregation inhibitor, Incentrom A
A series of Incentrom A analogs that inhibit the chromosome segregation process in yeast were synthesized and tested for their effects on chromosome stability and cell proliferation. Pharmacophore and structure-activity relationship of Incentrom A for the anti-yeast activity were established. (C) 2008 Elsevier Ltd. All rights reserved.
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Issue Date
- 2008-08
- Language
- English
- Article Type
- Article
- Keywords
CENTROMERE
- Citation
BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.18, no.16, pp.4670 - 4674
- ISSN
- 0960-894X
- Appears in Collection
- CH-Journal Papers(저널논문)
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