An efficient and eco-friendly approach to N-15-unsubstituted beta-lactams: N-15-labled synthons for taxol and its analogs

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An efficient and eco-friendly approach to N-unsubstituted beta -lactams has been developed using mostly water as the reaction medium. This methodology was applied to the synthesis of N-unsubstituted 3-hydroxy-4-phenyl-2-azetidinone derivatives (including N-15-labeled version) which are suitable precursors for the C-13 side chain of taxol and its analogs.
Publisher
KOREAN CHEMICAL SOC
Issue Date
2001-05
Language
English
Article Type
Article
Keywords

C-13 SIDE-CHAIN

Citation

BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.22, no.5, pp.493 - 498

ISSN
0253-2964
URI
http://hdl.handle.net/10203/83211
Appears in Collection
CBE-Journal Papers(저널논문)
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