Development of tripeptidyl farnesyltransferase inhibitors

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The first example of tripeptide inhibitors of farnesyltransferase with sub-micromolar inhibition activity was developed based on the fact that CVFM is not a substrate for farnesyltransferase. (C) 2002 Elsevier Science Ltd. All rights reserved.
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Issue Date
2002-06
Language
English
Article Type
Article
Keywords

FARNESYL-PROTEIN TRANSFERASE; ASYMMETRIC-SYNTHESIS; ALPHA-AMINO; ARTEMINOLIDE; ANALOG; DESIGN

Citation

BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.12, no.12, pp.1599 - 1602

ISSN
0960-894X
URI
http://hdl.handle.net/10203/80657
Appears in Collection
CH-Journal Papers(저널논문)
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