Regioselective alkylation and arylation at the 6-position of pyrimidine: Synthesis of 5-alkyl-6-arylmethyl-2,4-pyrimidinediones

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dc.contributor.authory.s.leeko
dc.contributor.authorKim, Yong Haeko
dc.date.accessioned2013-02-27T23:59:06Z-
dc.date.available2013-02-27T23:59:06Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued1999-
dc.identifier.citationSYNTHETIC COMMUNICATIONS, v.29, no.9, pp.1503 - 1517-
dc.identifier.issn0039-7911-
dc.identifier.urihttp://hdl.handle.net/10203/71609-
dc.description.abstract5-Alkyl-2,4,6-trichloropyrimidines reacted with various nucleophiles to afford the regioselectively 6-substituted pyrimidines as the major products in good yields, which were transformed to 5-alkyl-6-arylmethyl-2,4-pyrimidinediones of a key intermediate of MKC-442.-
dc.languageEnglish-
dc.publisherMARCEL DEKKER INC-
dc.subjectSELECTIVE ANTI-HIV-1 AGENTS-
dc.subjectANTI-HIV ACTIVITY-
dc.subject1-&lt-
dc.subject(2-HYDROXYETHOXY)METHYL&gt-
dc.subject-6-(PHENYLTHIO)THYMINE HEPT-
dc.subjectANTIVIRAL ACTIVITY-
dc.subjectANALOGS-
dc.subjectPOTENT-
dc.subjectDERIVATIVES-
dc.titleRegioselective alkylation and arylation at the 6-position of pyrimidine: Synthesis of 5-alkyl-6-arylmethyl-2,4-pyrimidinediones-
dc.typeArticle-
dc.identifier.wosid000079818100008-
dc.identifier.scopusid2-s2.0-0343565756-
dc.type.rimsART-
dc.citation.volume29-
dc.citation.issue9-
dc.citation.beginningpage1503-
dc.citation.endingpage1517-
dc.citation.publicationnameSYNTHETIC COMMUNICATIONS-
dc.identifier.doi10.1080/00397919908086130-
dc.contributor.nonIdAuthory.s.lee-
dc.type.journalArticleArticle-
dc.subject.keywordPlusSELECTIVE ANTI-HIV-1 AGENTS-
dc.subject.keywordPlusANTI-HIV ACTIVITY-
dc.subject.keywordPlus1-&lt-
dc.subject.keywordPlus(2-HYDROXYETHOXY)METHYL&gt-
dc.subject.keywordPlus-6-(PHENYLTHIO)THYMINE HEPT-
dc.subject.keywordPlusANTIVIRAL ACTIVITY-
dc.subject.keywordPlusANALOGS-
dc.subject.keywordPlusPOTENT-
dc.subject.keywordPlusDERIVATIVES-
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