A Cardiovascular Simulator for the Reproduction of Blood Pressure Waveform and Magnitude

Abstract

With the increase in life expectancy and advancements in medicine, the significance of cardiovascular health has gained prominence. Blood pressure is the most basic cardiovascular health indicator, containing various characteristics such as systolic blood pressure, diastolic blood pressure, augmentation point, and pulse wave propagation speed within the blood pressure waveform. Consequently, studies on estimating cardiovascular parameters from blood pressure waveforms are being actively conducted. However, limitations exist owing to biased clinical data primarily focused on elderly individuals and patients and difficulty in controlling variables. This study aimed to develop and evaluate a cardiovascular simulator replicating the human cardiovascular system, specifically focusing on studying blood pressure waveforms. The cardiovascular simulator successfully reproduced the blood pressure waveform and magnitude observed in middle-aged individuals. Additionally, the simulated blood pressure waveforms and pulse wave propagation speeds at various locations in the aorta were consistent with those of humans.