Fabrication and characterization of a trapezoidal electrode array for dielectrophoretic separation = 유전영동분리를 위한 사다리꼴 전극의 제작 및 평가에 대한 연구

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This paper presents a novel microfluidic device for dielectrophoretic separation based on a trapezoidal electrode array (TEA). In this methodology, particles with different dielectric properties are separated by a microfluidic system that is composed of the TEA for the dielectrophoretic deflection of particles under the negative dielectrophoresis (DEP) and poly(dimethylsiloxane) (PDMS) microfluidic channel with a sinuous and expanded region. Polystyrene microparticles are exposed to an electric field generated from the TEA in the microfluidic channel and dielectrophoretically focused to make all of them lined up to one sidewall. When these particles arrive at the region of another TEA for dielectrophoretic separation, they are separated having different positions along the perpendicular direction to the fluid flow due to their different dielectrophoretic velocities. To evaluate the separation process and performance, both the effect of the flow rate on dielectrophoretic focusing and the influence of the number of trapezoidal electrodes on dielectrophoretic separation are investigated. Now that this method utilizes the TEA as a source of DEP, non-specific particle adhering to the electrode surface can be prevented: conventional separation approaches depending on the positive DEP force suffer from this problem. In addition, since various particle types are continuously separated, this method can be easily applicable to separation and analysis of various dielectric particles with high particle recovery and selectivity.
Advisors
Park, Je-Kyunresearcher박제균researcher
Description
한국과학기술원 : 바이오시스템학과,
Publisher
한국과학기술원
Issue Date
2005
Identifier
249537/325007  / 020033956
Language
eng
Description

학위논문(석사) - 한국과학기술원 : 바이오시스템학과, 2005.8, [ ix, 46 p. ]

Keywords

Microfluidics; Dielectrophoresis; Particle separation; 입자분리; 미세유체역학; 유전영동

URI
http://hdl.handle.net/10203/27110
Link
http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=249537&flag=dissertation
Appears in Collection
BiS-Theses_Master(석사논문)
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