Fluorescence polarization-based detection of cancer-related mutations using target-initiated rolling circle amplification

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dc.contributor.authorKwon, Woo Youngko
dc.contributor.authorCha, Byung Seokko
dc.contributor.authorKim, Seokjoonko
dc.contributor.authorHwang, Sung Hyunko
dc.contributor.authorKim, Ji Minko
dc.contributor.authorKalimuthu, Kalishwaralalko
dc.contributor.authorPark, Hyun Gyuko
dc.contributor.authorPark, Ki Sooko
dc.date.accessioned2019-07-29T06:20:34Z-
dc.date.available2019-07-29T06:20:34Z-
dc.date.created2019-07-29-
dc.date.created2019-07-29-
dc.date.issued2019-07-
dc.identifier.citationANALYST, v.144, no.14, pp.4149 - 4152-
dc.identifier.issn0003-2654-
dc.identifier.urihttp://hdl.handle.net/10203/263876-
dc.description.abstractWe devised a new method to detect cancer-related mutations based on target-initiated rolling circle amplification in combination with fluorescence polarization. We then applied this method to identify the presence of KRAS G13D and G12D, two of the most frequent mutations found in colorectal cancer patients, demonstrating high sensitivity and specificity.-
dc.languageEnglish-
dc.publisherROYAL SOC CHEMISTRY-
dc.titleFluorescence polarization-based detection of cancer-related mutations using target-initiated rolling circle amplification-
dc.typeArticle-
dc.identifier.wosid000474643700002-
dc.identifier.scopusid2-s2.0-85068614662-
dc.type.rimsART-
dc.citation.volume144-
dc.citation.issue14-
dc.citation.beginningpage4149-
dc.citation.endingpage4152-
dc.citation.publicationnameANALYST-
dc.identifier.doi10.1039/c9an00429g-
dc.contributor.localauthorPark, Hyun Gyu-
dc.contributor.nonIdAuthorKwon, Woo Young-
dc.contributor.nonIdAuthorCha, Byung Seok-
dc.contributor.nonIdAuthorKim, Seokjoon-
dc.contributor.nonIdAuthorHwang, Sung Hyun-
dc.contributor.nonIdAuthorKim, Ji Min-
dc.contributor.nonIdAuthorKalimuthu, Kalishwaralal-
dc.contributor.nonIdAuthorPark, Ki Soo-
dc.description.isOpenAccessN-
dc.type.journalArticleArticle-
dc.subject.keywordPlusBIOMARKERS-
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