Epitranscriptomes in the Adult Mammalian Brain: Dynamic Changes Regulate Behavior

Abstract

Epitranscriptomic modification of mRNA affects its metabolism and has recently been shown to regulate brain development. Two studies in this issue of Neuron, Koranda et al. (2018) and Engel et al. (2018), uncover dynamic and critical roles of m(6) A/m RNA modifications in the adult mammalian brain in regulating physiological and stress-induced behaviors.