HMGB1: LPS Delivery Vehicle for Caspase-11-Mediated Pyroptosis

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Recognition of cytoplasmic lipopolysaccharide (LPS) by caspase-11 leads to pyroptosis and secretion of inflammatory mediators. In this issue of Immunity, Deng et al. (2018) report that high-mobility group box 1 (HMGB1) secreted by hepatocytes delivers extracellular LPS into the cytoplasm and mediates pyroptosis.
Publisher
CELL PRESS
Issue Date
2018-10
Language
English
Article Type
Editorial Material
Citation

IMMUNITY, v.49, no.4, pp.582 - 584

ISSN
1074-7613
DOI
10.1016/j.immuni.2018.09.021
URI
http://hdl.handle.net/10203/246559
Appears in Collection
MSE-Journal Papers(저널논문)
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