DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Miji | ko |
dc.contributor.author | Kim, Hyeseung | ko |
dc.contributor.author | Kim, Hyunwoo | ko |
dc.contributor.author | Chin, Jik | ko |
dc.date.accessioned | 2018-01-22T09:01:11Z | - |
dc.date.available | 2018-01-22T09:01:11Z | - |
dc.date.created | 2017-12-26 | - |
dc.date.created | 2017-12-26 | - |
dc.date.created | 2017-12-26 | - |
dc.date.issued | 2017-12 | - |
dc.identifier.citation | JOURNAL OF ORGANIC CHEMISTRY, v.82, no.23, pp.12050 - 12058 | - |
dc.identifier.issn | 0022-3263 | - |
dc.identifier.uri | http://hdl.handle.net/10203/237683 | - |
dc.description.abstract | The stereoselective synthesis of mixed alkyl-aryl vicinal diamines was demonstrated by the use of 1,2-bis(2-hydroxyphenyl)-1,2-diaminoethene (hpen). A sequential addition of aryl and alkyl aldehyde to hpen gave a fused imidazolidinedihydro-1,3-oxazine ring stereoselectively, which undergoes the diaza-Cope rearrangement to provide mixed vicinal diimines at elevated temperature in good yields and excellent stereoselectivity. We also showed that (+)-CP-99,994 can be readily prepared by the diaza-Cope rearrangement in overall 42% yield. | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Synthesis of Enantiopure Mixed Alkyl-Aryl Vicinal Diamines by the Diaza-Cope Rearrangement: A Synthesis of (+)-CP-99,994 | - |
dc.type | Article | - |
dc.identifier.wosid | 000417342300008 | - |
dc.identifier.scopusid | 2-s2.0-85036497644 | - |
dc.type.rims | ART | - |
dc.citation.volume | 82 | - |
dc.citation.issue | 23 | - |
dc.citation.beginningpage | 12050 | - |
dc.citation.endingpage | 12058 | - |
dc.citation.publicationname | JOURNAL OF ORGANIC CHEMISTRY | - |
dc.identifier.doi | 10.1021/acs.joc.7b01751 | - |
dc.contributor.localauthor | Kim, Hyunwoo | - |
dc.contributor.nonIdAuthor | Kim, Hyeseung | - |
dc.contributor.nonIdAuthor | Chin, Jik | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | TERT-BUTANESULFINYL IMINES | - |
dc.subject.keywordPlus | AZA-HENRY REACTION | - |
dc.subject.keywordPlus | ASYMMETRIC-SYNTHESIS | - |
dc.subject.keywordPlus | ENANTIOSELECTIVE SYNTHESIS | - |
dc.subject.keywordPlus | STEREOSPECIFIC SYNTHESIS | - |
dc.subject.keywordPlus | ENANTIOMERICALLY PURE | - |
dc.subject.keywordPlus | CONJUGATED DIENES | - |
dc.subject.keywordPlus | CHIRAL DIAMINES | - |
dc.subject.keywordPlus | MOTHER DIAMINE | - |
dc.subject.keywordPlus | (+)-L-733,060 | - |
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