DSpace at KOASAS
College of Life Science and Bioengineering(생명과학기술대학)Dept. of Biological Sciences(생명과학과)BS-Journal Papers(저널논문)

Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia

Cited 101 time in webofscience Cited 94 time in scopus
  • Hit : 761
  • Download : 0
Export
DC FieldValueLanguage
dc.contributor.authorBerglund, Eric D.ko
dc.contributor.authorLiu, Tieminko
dc.contributor.authorKong, Xingxingko
dc.contributor.authorSohn, Jong Wooko
dc.contributor.authorVong, Linhko
dc.contributor.authorDeng, Zhuoko
dc.contributor.authorLee, Charlotte E.ko
dc.contributor.authorLee, Syannko
dc.contributor.authorWilliams, Kevin W.ko
dc.contributor.authorOlson, David P.ko
dc.contributor.authorScherer, Philipp E.ko
dc.contributor.authorLowell, Bradford B.ko
dc.contributor.authorElmquist, Joel K.ko
dc.date.accessioned2015-03-27T08:06:30Z-
dc.date.available2015-03-27T08:06:30Z-
dc.date.created2014-07-29-
dc.date.created2014-07-29-
dc.date.issued2014-07-
dc.identifier.citationNATURE NEUROSCIENCE, v.17, no.7, pp.911 - 913-
dc.identifier.issn1097-6256-
dc.identifier.urihttp://hdl.handle.net/10203/194547-
dc.description.abstractWhether melanocortin 4 receptors (MC4Rs) in extra-hypothalamic neurons, including cholinergic autonomic pre-ganglionic neurons, are required to control energy and glucose homeostasis is unclear. We found that MC4Rs in sympathetic, but not parasympathetic, pre-ganglionic neurons were required to regulate energy expenditure and body weight, including thermogenic responses to diet and cold exposure and 'beiging' of white adipose tissue. Deletion of Mc4r genes in both sympathetic and parasympathetic cholinergic neurons impaired glucose homeostasis.-
dc.languageEnglish-
dc.publisherNATURE PUBLISHING GROUP-
dc.subjectBROWN ADIPOSE-TISSUE-
dc.subjectADAPTIVE THERMOGENESIS-
dc.subjectGLUCOSE-HOMEOSTASIS-
dc.subjectOBESITY-
dc.subjectACTIVATION-
dc.subjectCIRCUITRY-
dc.subjectRESPONSES-
dc.subjectHUMANS-
dc.subjectMICE-
dc.titleMelanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia-
dc.typeArticle-
dc.identifier.wosid000338097200007-
dc.identifier.scopusid2-s2.0-84903381007-
dc.type.rimsART-
dc.citation.volume17-
dc.citation.issue7-
dc.citation.beginningpage911-
dc.citation.endingpage913-
dc.citation.publicationnameNATURE NEUROSCIENCE-
dc.identifier.doi10.1038/nn.3737-
dc.contributor.localauthorSohn, Jong Woo-
dc.contributor.nonIdAuthorBerglund, Eric D.-
dc.contributor.nonIdAuthorLiu, Tiemin-
dc.contributor.nonIdAuthorKong, Xingxing-
dc.contributor.nonIdAuthorVong, Linh-
dc.contributor.nonIdAuthorDeng, Zhuo-
dc.contributor.nonIdAuthorLee, Charlotte E.-
dc.contributor.nonIdAuthorLee, Syann-
dc.contributor.nonIdAuthorWilliams, Kevin W.-
dc.contributor.nonIdAuthorOlson, David P.-
dc.contributor.nonIdAuthorScherer, Philipp E.-
dc.contributor.nonIdAuthorLowell, Bradford B.-
dc.contributor.nonIdAuthorElmquist, Joel K.-
dc.type.journalArticleArticle-
dc.subject.keywordPlusBROWN ADIPOSE-TISSUE-
dc.subject.keywordPlusADAPTIVE THERMOGENESIS-
dc.subject.keywordPlusGLUCOSE-HOMEOSTASIS-
dc.subject.keywordPlusOBESITY-
dc.subject.keywordPlusACTIVATION-
dc.subject.keywordPlusCIRCUITRY-
dc.subject.keywordPlusRESPONSES-
dc.subject.keywordPlusHUMANS-
dc.subject.keywordPlusMICE-
Appears in Collection
BS-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 101 items in WoS Click to see citing articles in records_button

Display Simple Item Record

qr_code

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


rss_1.0 rss_2.0 atom_1.0