Immobilization of Antibody on a Cyclic Olefin Copolymer Surface with Functionalizable, Non-Biofouling Poly[Oligo(Ethylene Glycol) Methacrylate]

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We report a perfluoroaryl azide-based photoreaction for synthesizing functionalizable and nonbiofouling poly[oligo(ethylene glycol) methacrylate] (pOEGMA) films on a chemically inert COC substrate, and an estimation of a surface coverage of the antibody immobilized onto the surface with the immuno-gold nanoparticles. The processes were confirmed by water contact angle measurement, FT-IA spectroscopy, and FE-SEM. The strategy demonstrated in this work could be applied to functionalizations of other polymeric materials and determination of the binding capacity of analytes in biosensors and microfluidic devices.
Publisher
AMER SCIENTIFIC PUBLISHERS
Issue Date
2015-02
Language
English
Article Type
Article
Keywords

MICROFLUIDIC DEVICES; FABRICATION; CHANNELS

Citation

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v.15, no.2, pp.1767 - 1770

ISSN
1533-4880
DOI
10.1166/jnn.2015.9335
URI
http://hdl.handle.net/10203/193874
Appears in Collection
CH-Journal Papers(저널논문)
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