A new helicase assay based on graphene oxide for anti-viral drug development

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Recently, graphene oxide (GO), one of the carbon nanomaterials, has received much attention due to its unique physical and chemical properties and high potential in many research areas, including applications as a biosensor and drug delivery vehicle. Various GO-based biosensors have been developed, largely based on its surface adsorption properties for detecting biomolecules, such as nucleotides and peptides, and real-time monitoring of enzymatic reactions. In this review, we discuss recent advances in GO-based biosensors focusing on a novel assay platform for helicase activity, which was also employed in high-throughput screening to discover selective helicase inhibitors.
Publisher
KOREAN SOC MOLECULAR & CELLULAR BIOLOGY
Issue Date
2013-04
Language
English
Article Type
Review
Citation

MOLECULES AND CELLS, v.35, no.4, pp.269 - 273

ISSN
1016-8478
DOI
10.1007/s10059-013-0066-1
URI
http://hdl.handle.net/10203/174058
Appears in Collection
CH-Journal Papers(저널논문)
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